在一只虹彩吸蜜鹦鹉（Trichoglossus moluccanus）粪便中发现的一种新型小核糖核酸病毒与禽肝病毒属成员关系密切。
A novel picornavirus in feces of a rainbow lorikeet (Trichoglossus moluccanus) shows a close relationship to members of the genus Avihepatovirus.
作者信息
Wang Haoning, Yang Shixing, Shan Tongling, Wang Xiaolong, Deng Xutao, Delwart Eric, Zhang Wen
机构信息
College of Wildlife Resource, Northeast Forestry University, Harbin, Heilongjiang, China.
Department of Swine Infectious Disease, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, China.
出版信息
Arch Virol. 2019 Jul;164(7):1911-1914. doi: 10.1007/s00705-019-04246-5. Epub 2019 Apr 13.
A novel picornavirus, named "lorikeet picornavirus 1" (LoPV-1), was detected in a fecal sample from rainbow lorikeets using viral metagenomic analysis, and its complete genome sequence was determined and analyzed. The genome of LoPV-1 is 7862 nt long, including a 617-nt 5' UTR, a type IV IRES 5'UTR with an '8-like' motif, a 7032-nt polyprotein ORF, and a 213-nt 3' UTR. Phylogenetic analysis and pairwise asequence comparisons based on the amino acid sequences of P1, P2, and P3 indicated that LoPV-1 showed the closest relationship to two picornaviruses that were isolated recently from red-crowned cranes and clustered together with members of the genus Avihepatovirus.
通过病毒宏基因组分析，在彩虹吸蜜鹦鹉的粪便样本中检测到一种新型小RNA病毒，命名为“吸蜜鹦鹉小RNA病毒1”（LoPV-1），并对其完整基因组序列进行了测定和分析。LoPV-1的基因组长度为7862 nt，包括一个617 nt的5'UTR、一个具有“8样”基序的IV型IRES 5'UTR、一个7032 nt的多聚蛋白开放阅读框和一个213 nt的3'UTR。基于P1、P2和P3氨基酸序列的系统发育分析和序列两两比较表明，LoPV-1与最近从丹顶鹤中分离出的两种小RNA病毒关系最为密切，并与禽肝炎病毒属的成员聚集在一起。
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