[2017年河南省首例输入性基孔肯雅热病例的流行病学及病原学特征分析]

[Analysis on the epidemiology and etiology characteristics of first imported Chikungunya fever case in Henan Province in 2017].

作者信息

Li X L, Li Y, Wang R L, Zhang B F, Su J, Guo D C, Xu B L, Huang X Y

机构信息

Institute for Infectious Disease Control and Prevention, Henan Center for Disease Control and Prevention, Zhengzhou 450016, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Apr 6;53(4):415-418. doi: 10.3760/cma.j.issn.0253-9624.2019.04.017.

DOI:10.3760/cma.j.issn.0253-9624.2019.04.017

PMID:30982279

Abstract

To study the epidemiology and etiology characteristics of first imported Chikungunya fever case in Henan province, China, 2017. The patient was confirmed by Chikungunya virus (CHIKV) infected as CHIKV ribonucleotide was continuously detected in his serum specimens. BHK-21 cell line was used for virus isolation, the strain was named CHIKV/Henan001/2017. CHIKV/Henan001/2017 belonged to genotype ECSA. The highest ribonucleotide homology sequence of highly conserved region E1 with CHIKV/Henan001/2017 was hk02 strain (99.8%), who was an imported strain to Hong Kong, China, 2016. Epidemiological information and laboratory testing confirmed it was an imported Chikungunya fever case in Henan province, 2017. No secondary case has been reported.

摘要

为研究2017年中国河南省首例输入性基孔肯雅热病例的流行病学和病因学特征。该患者经确诊感染基孔肯雅病毒（CHIKV），因其血清标本中持续检测到CHIKV核糖核苷酸。采用BHK-21细胞系进行病毒分离，该毒株命名为CHIKV/Henan001/2017。CHIKV/Henan001/2017属于ECSA基因型。与CHIKV/Henan001/2017高度保守区E1核糖核苷酸同源性最高的序列是hk02毒株（99.8%），其为2016年中国香港的输入毒株。流行病学信息和实验室检测证实这是2017年河南省的一例输入性基孔肯雅热病例。未报告二代病例。