Ruili Center for Disease Control and Prevention, Ruili, Yunnan, People's Republic of China.
Center for Disease Control and Prevention of Southern Theater Command, Kunming, Yunnan Province, 650118, People's Republic of China.
Arch Virol. 2021 May;166(5):1455-1462. doi: 10.1007/s00705-021-05005-1. Epub 2021 Mar 11.
During the dengue epidemic in Yunnan Province, China, during 2019, a concurrent outbreak of chikungunya occurred in the city of Ruili, which is located in the southwest of the province, adjacent to Myanmar. As part of this outbreak, three neonatal cases of infection with indigenous chikungunya virus from mother-to-child (vertical) transmission were observed. Isolates of chikungunya virus were obtained from 37 serum samples of patients with chikungunya during this outbreak, and a phylogenetic analysis of these isolates revealed that they belong to the Indian Ocean subclade of the East/Central/South African genotype. The E1 genes of these viruses did not harbor the A226V mutation.
在中国云南省 2019 年登革热疫情期间，该省西南部与缅甸接壤的瑞丽市同时暴发基孔肯雅热疫情。此次疫情中观察到 3 例新生儿感染本土基孔肯雅病毒的垂直（母婴）传播病例。从疫情中 37 例基孔肯雅热患者的血清样本中分离出基孔肯雅病毒，对这些分离株进行的系统进化分析表明，它们属于东/中/南非基因型印度洋分支。这些病毒的 E1 基因不含有 A226V 突变。
