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Extracellular vesicles, the liquid biopsy of the future.

作者信息

Eguchi Akiko, Kostallari Enis, Feldstein Ariel E, Shah Vijay H

机构信息

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Mie University, 2-174 Edobashi, Tsu, Mie, Japan; JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

出版信息

J Hepatol. 2019 Jun;70(6):1292-1294. doi: 10.1016/j.jhep.2019.01.030. Epub 2019 Apr 12.

DOI:10.1016/j.jhep.2019.01.030
PMID:30982591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7094760/
Abstract
摘要

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本文引用的文献

1
Subpopulations of extracellular vesicles and their therapeutic potential.细胞外囊泡亚群及其治疗潜力。
Mol Aspects Med. 2018 Apr;60:1-14. doi: 10.1016/j.mam.2018.02.002. Epub 2018 Feb 16.
2
Hepatic stellate cell-derived platelet-derived growth factor receptor-alpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.肝星状细胞衍生的血小板衍生生长因子受体-α富集的细胞外囊泡通过 SHP2 促进小鼠肝纤维化。
Hepatology. 2018 Jul;68(1):333-348. doi: 10.1002/hep.29803. Epub 2018 May 10.
3
Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.酒精性肝病胃灌注模型中肝细胞释放的细胞外囊泡含有一种可在血液中检测到的微小RNA条形码。
Hepatology. 2017 Feb;65(2):475-490. doi: 10.1002/hep.28838. Epub 2016 Nov 10.
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Extracellular vesicles in liver pathobiology: Small particles with big impact.肝脏病理生物学中的细胞外囊泡：影响重大的小颗粒。
Hepatology. 2016 Dec;64(6):2219-2233. doi: 10.1002/hep.28814. Epub 2016 Oct 20.
5
Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ.脂质诱导的肝细胞衍生细胞外囊泡通过靶向PPAR-γ的微小RNA调节肝星状细胞。
Cell Mol Gastroenterol Hepatol. 2015 Nov 1;1(6):646-663.e4. doi: 10.1016/j.jcmgh.2015.07.007.
6
Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles.酒精通过半胱天冬酶依赖性肝细胞衍生的含CD40L细胞外囊泡的释放来刺激巨噬细胞活化。
J Hepatol. 2016 Mar;64(3):651-60. doi: 10.1016/j.jhep.2015.11.020. Epub 2015 Nov 26.
7
Emerging techniques in the isolation and characterization of extracellular vesicles and their roles in cancer diagnostics and prognostics.细胞外囊泡分离与表征的新兴技术及其在癌症诊断和预后中的作用。
Analyst. 2016 Jan 21;141(2):371-81. doi: 10.1039/c5an01775k.
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Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes.混合谱系激酶3介导脂毒性肝细胞释放携带C-X-C基序配体10的趋化性细胞外囊泡。
Hepatology. 2016 Mar;63(3):731-44. doi: 10.1002/hep.28252. Epub 2015 Dec 11.
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Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate.肝细胞外泌体通过1-磷酸鞘氨醇介导肝脏修复和再生。
J Hepatol. 2016 Jan;64(1):60-8. doi: 10.1016/j.jhep.2015.07.030. Epub 2015 Aug 5.
10
Single-step isolation of extracellular vesicles by size-exclusion chromatography.通过大小排阻色谱法一步分离细胞外囊泡。
J Extracell Vesicles. 2014 Sep 8;3. doi: 10.3402/jev.v3.23430. eCollection 2014.