Department of Dermatology, Medical Faculty, Ege University, Izmir, Turkey.
Department of Pathology, Medical Faculty, Ege University, Izmir, Turkey.
Int Wound J. 2019 Aug;16(4):946-950. doi: 10.1111/iwj.13126. Epub 2019 Apr 14.
Extranodal NK/T cell lymphoma (ENKTL) is a rare form of non-Hodgkin lymphoma. It mostly occurs in the upper respiratory tract. Cutaneous involvement can be seen among the extranasal ENKTLs. After solid organ and haematopoietic stem cell transplantation, post-transplantation lymphoproliferative disease because of immunosuppressive therapy is usually B cell-derived; T and NK/T cell-derived disease is rarely seen. A 43-year-old female patient who had renal transplantation 14 years ago presented with cutaneous ulceration and subcutaneous nodules located in the abdomen. The patient was diagnosed with ENKTL, nasal type. Although it is rare, ENKTL nasal type is a lymphoproliferative disease that should be considered in the differential diagnosis of ulcerated cutaneous tumoural lesions.
结外 NK/T 细胞淋巴瘤(ENKTL)是一种罕见的非霍奇金淋巴瘤。它主要发生在上呼吸道。结外鼻型 ENKTL 可伴有皮肤累及。在实体器官和造血干细胞移植后,由于免疫抑制治疗,移植后淋巴组织增生性疾病通常为 B 细胞来源;T 和 NK/T 细胞来源的疾病很少见。一位 43 岁的女性患者,14 年前接受了肾移植,目前出现腹部皮肤溃疡和皮下结节。患者被诊断为鼻型 ENKTL。尽管罕见,但鼻型 ENKTL 是一种淋巴组织增生性疾病,在鉴别诊断溃疡性皮肤肿瘤病变时应考虑到这一点。