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拨开中度风险(亚大面积)肺栓塞的迷雾:全剂量、低剂量还是不进行溶栓治疗?

Lifting the fog in intermediate-risk (submassive) PE: full dose, low dose, or no thrombolysis?

作者信息

Bhamani Amyn, Pepke-Zaba Joanna, Sheares Karen

机构信息

Department of Respiratory Medicine, Basildon and Thurrock University Hospital, Basildon, Essex, SS16 5NL.

Pulmonary Vascular Diseases Unit, Royal Papworth Hospital, Cambridge, CB23 3RE.

出版信息

F1000Res. 2019 Mar 25;8. doi: 10.12688/f1000research.17861.1. eCollection 2019.

Abstract

Acute pulmonary embolism (PE) is a disease frequently encountered in clinical practice. While the management of haemodynamically stable, low risk patients with acute PE is well established, managing intermediate disease often presents a therapeutic dilemma. In this review, we discuss the various therapeutic options available in this patient group. This includes thrombolysis, surgical embolectomy and catheter directed techniques. We have also explored the role of specialist PE response teams in the management of such patients. ​.

摘要

急性肺栓塞(PE)是临床实践中常见的疾病。虽然血流动力学稳定的急性PE低风险患者的管理方法已得到充分确立,但对中度风险疾病的管理常常带来治疗困境。在本综述中,我们讨论了该患者群体可用的各种治疗选择。这包括溶栓、外科血栓切除术和导管定向技术。我们还探讨了专业PE应对团队在这类患者管理中的作用。

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