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肥胖中的高血压:新见解

Hypertension in Obesity: Novel Insights.

作者信息

Natsis Michail, Antza Christina, Doundoulakis Ioannis, Stabouli Stella, Kotsis Vasilios

机构信息

3rd Department of Internal Medicine, Hypertension-24h ABPM ESH Center of Excellence, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

1st Department of Pediatrics, Hippokration Hospital, Thessaloniki, Greece.

出版信息

Curr Hypertens Rev. 2020;16(1):30-36. doi: 10.2174/1573402115666190415154603.

Abstract

BACKGROUND

The relationship between obesity and hypertension has been established in both adults and children. The combination of obesity, hypertension and other cardiovascular risk factors significantly increases the likelihood of adverse cardiovascular effects and raises concerns about aggressive treatment strategies.

OBJECTIVE

Despite the impressive elements which indicate an important role for excessive weight gain in increasing blood pressure, not all obese patients are hypertensive. A subgroup of obese people may not develop hypertension. Furthermore, masked hypertension occurs more common among obese patients, and body fat distribution has a major role in the development of hypertension.

METHOD

We conducted a research of the relevant literature regarding obesity-induced hypertension and possible treatment strategies.

RESULTS

Successful weight loss is correlated with blood pressure reduction and requires a multidisciplinary approach that includes personalized dietary interventions combined with regular exercise and cognitive behavioral therapy.

CONCLUSION

Pharmacological therapy may be considered as part of a comprehensive obesity management strategy. More research and new treatment therapies are required in this field.

摘要

背景

肥胖与高血压之间的关系在成人和儿童中均已得到证实。肥胖、高血压及其他心血管危险因素并存会显著增加发生不良心血管事件的可能性,并引发对积极治疗策略的关注。

目的

尽管有诸多因素表明体重过度增加在血压升高中起重要作用,但并非所有肥胖患者都患有高血压。一部分肥胖人群可能不会患高血压。此外,隐匿性高血压在肥胖患者中更为常见,且体脂分布在高血压的发生中起主要作用。

方法

我们对有关肥胖诱导型高血压及可能的治疗策略的相关文献进行了研究。

结果

成功减重与血压降低相关,且需要采取多学科方法,包括个性化饮食干预、定期运动和认知行为疗法。

结论

药物治疗可被视为综合肥胖管理策略的一部分。该领域需要更多研究和新的治疗方法。

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