Suppr超能文献

袖状胃切除术治疗认知障碍或发育障碍的青少年

Sleeve Gastrectomy for Youth With Cognitive Impairment or Developmental Disability.

机构信息

Center for Translational Research, Children's National Health System, Washington, District of Columbia;

School of Medicine and Health Sciences, The George Washington University, Washington, District of Columbia; and.

出版信息

Pediatrics. 2019 May;143(5). doi: 10.1542/peds.2018-2908. Epub 2019 Apr 15.

Abstract

BACKGROUND AND OBJECTIVES

Youth with cognitive impairment or developmental disability (CI/DD) face higher rates of obesity and secondary medical issues. Bariatric surgery may be a helpful tool for health improvement because it has been shown efficacious for adolescents. We aim to contribute to literature regarding bariatric surgery for adolescents with CI/DD and explore the association between cognitive functioning and weight loss outcomes.

METHODS

Adolescents ( = 64) received a preoperative psychological evaluation, including cognitive assessment, and bariatric surgery at 1 weight loss program between 2010 and 2017. For these adolescents with measured cognitive performance, CI/DD was defined by an IQ <80 or previous diagnosis. In analyses, we compared adolescents with and without CI/DD. Structural equation modeling was used to assess the impact of cognitive functioning on weight loss 3 to 24 months postsurgery.

RESULTS

There were no significant differences between adolescents with or without CI/DD in terms of preoperative BMI, age, and sex. Having CI/DD did not significantly impact weight loss or weight loss trajectory in the 2 years after surgery, although modeling revealed a trend toward individuals with CI/DD losing more weight over time. Similarly, intelligence scores did not predict weight loss after surgery.

CONCLUSIONS

Bariatric surgery may be a helpful tool for adolescents with severe obesity and CI/DD. They could benefit from the surgery as much as those with typical development, and having CI/DD should not be used as a criterion to deny surgery. Continuing research with this population can be used to determine long-term outcomes in addition to defining best practices.

摘要

背景和目的

患有认知障碍或发育障碍(CI/DD)的年轻人肥胖率和继发医疗问题较高。减重手术可能是改善健康的有效工具,因为它已被证明对青少年有效。我们旨在为患有 CI/DD 的青少年的减重手术相关文献做出贡献,并探索认知功能与减重效果之间的关联。

方法

2010 年至 2017 年间,64 名青少年在 1 个减重计划中接受了术前心理评估,包括认知评估和减重手术。对于这些具有测量认知表现的青少年,如果智商<80 或之前有过诊断,则定义为 CI/DD。在分析中,我们比较了有无 CI/DD 的青少年。结构方程模型用于评估认知功能对术后 3 至 24 个月减重的影响。

结果

有无 CI/DD 的青少年在术前 BMI、年龄和性别方面无显著差异。在手术后的 2 年内,患有 CI/DD 并不会显著影响减重或减重轨迹,尽管模型显示 CI/DD 患者随着时间的推移体重减轻更多。同样,智力评分并不能预测手术后的减重效果。

结论

减重手术可能是严重肥胖和 CI/DD 青少年的有用工具。他们可以像典型发育的青少年一样从手术中受益,而不应将 CI/DD 作为拒绝手术的标准。对该人群的进一步研究可以用来确定长期结果,除了确定最佳实践之外。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验