Center for Translational Research, Children's National Health System, Washington, District of Columbia;
School of Medicine and Health Sciences, The George Washington University, Washington, District of Columbia; and.
Pediatrics. 2019 May;143(5). doi: 10.1542/peds.2018-2908. Epub 2019 Apr 15.
Youth with cognitive impairment or developmental disability (CI/DD) face higher rates of obesity and secondary medical issues. Bariatric surgery may be a helpful tool for health improvement because it has been shown efficacious for adolescents. We aim to contribute to literature regarding bariatric surgery for adolescents with CI/DD and explore the association between cognitive functioning and weight loss outcomes.
Adolescents ( = 64) received a preoperative psychological evaluation, including cognitive assessment, and bariatric surgery at 1 weight loss program between 2010 and 2017. For these adolescents with measured cognitive performance, CI/DD was defined by an IQ <80 or previous diagnosis. In analyses, we compared adolescents with and without CI/DD. Structural equation modeling was used to assess the impact of cognitive functioning on weight loss 3 to 24 months postsurgery.
There were no significant differences between adolescents with or without CI/DD in terms of preoperative BMI, age, and sex. Having CI/DD did not significantly impact weight loss or weight loss trajectory in the 2 years after surgery, although modeling revealed a trend toward individuals with CI/DD losing more weight over time. Similarly, intelligence scores did not predict weight loss after surgery.
Bariatric surgery may be a helpful tool for adolescents with severe obesity and CI/DD. They could benefit from the surgery as much as those with typical development, and having CI/DD should not be used as a criterion to deny surgery. Continuing research with this population can be used to determine long-term outcomes in addition to defining best practices.
患有认知障碍或发育障碍(CI/DD)的年轻人肥胖率和继发医疗问题较高。减重手术可能是改善健康的有效工具,因为它已被证明对青少年有效。我们旨在为患有 CI/DD 的青少年的减重手术相关文献做出贡献,并探索认知功能与减重效果之间的关联。
2010 年至 2017 年间,64 名青少年在 1 个减重计划中接受了术前心理评估,包括认知评估和减重手术。对于这些具有测量认知表现的青少年,如果智商<80 或之前有过诊断,则定义为 CI/DD。在分析中,我们比较了有无 CI/DD 的青少年。结构方程模型用于评估认知功能对术后 3 至 24 个月减重的影响。
有无 CI/DD 的青少年在术前 BMI、年龄和性别方面无显著差异。在手术后的 2 年内,患有 CI/DD 并不会显著影响减重或减重轨迹,尽管模型显示 CI/DD 患者随着时间的推移体重减轻更多。同样,智力评分并不能预测手术后的减重效果。
减重手术可能是严重肥胖和 CI/DD 青少年的有用工具。他们可以像典型发育的青少年一样从手术中受益,而不应将 CI/DD 作为拒绝手术的标准。对该人群的进一步研究可以用来确定长期结果,除了确定最佳实践之外。