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半骨盆切除术治疗盆腔肿瘤的并发症及成本分析

COMPLICATIONS AND COST ANALYSIS OF HEMIPELVECTOMY FOR THE TREATMENT OF PELVIC TUMORS.

作者信息

Benatto Mariana Tedeschi, Hussein Amira Mohamede, Gava Nelson Fabrício, Maranho Daniel Augusto, Engel Edgard Eduard

机构信息

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Hospital Clínica de Ribeirão Preto, Centro de Reabilitação, Ribeirão Preto, SP, Brazil.

Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Biomecênica, Medicina e Reabilitaçaõ do Sistema Locomotor, Ribeirão Preto, SP, Brazil.

出版信息

Acta Ortop Bras. 2019 Mar-Apr;27(2):104-107. doi: 10.1590/1413-785220192702206721.

Abstract

OBJECTIVE

Hemipelvectomy is a complex surgery with a high complication rate. Here, we aimed to identify factors related to the onset of complications and calculate their impacts on hospital costs.

METHODS

We evaluated 31 consecutive patients who underwent hemipelvectomy between 1999 and 2015. We assessed the clinical and radiographic data to determine the patients' demographic factors, tumor and surgical characteristics, and complications. The individual hospital stays and financial balances were assessed up to 6 months following the index surgery.

RESULTS

The overall complication rate was 61% (19/31). Infection was the most prevalent complication (36%). Immediate postoperative death occurred in 5/31 patients (16%); another 5 (16%) died after hospital discharge due to disease progression. Histological grade, previous surgery, and previous radiotherapy were not associated with complications or infection. Acetabular resections, bone reconstruction, and longer operative times were associated with infection, whereas older age, pelvic organ involvement, and comorbidities were associated with immediate postoperative death. Complications and infection were associated with 4.8- and 5.9-fold increases in hospital costs, respectively.

CONCLUSIONS

Acetabular resection and bone reconstruction are important factors that increase short-term complication rates, infection rates, and hospital costs. Mortality was associated with older age and adjacent pelvic tumor progression.

摘要

目的

半骨盆切除术是一种复杂的手术,并发症发生率较高。在此,我们旨在确定与并发症发生相关的因素,并计算它们对医院成本的影响。

方法

我们评估了1999年至2015年间连续接受半骨盆切除术的31例患者。我们评估了临床和影像学数据,以确定患者的人口统计学因素、肿瘤和手术特征以及并发症。在首次手术之后长达6个月的时间里,对患者的住院时间和财务收支情况进行了评估。

结果

总体并发症发生率为61%(19/31)。感染是最常见的并发症(36%)。5/31例患者(16%)术后立即死亡;另有5例(16%)在出院后因疾病进展死亡。组织学分级、既往手术和既往放疗与并发症或感染无关。髋臼切除术、骨重建和较长的手术时间与感染有关,而年龄较大、盆腔器官受累和合并症与术后立即死亡有关。并发症和感染分别使医院成本增加4.8倍和5.9倍。

结论

髋臼切除术和骨重建是增加短期并发症发生率、感染率和医院成本的重要因素。死亡率与年龄较大和盆腔邻近肿瘤进展有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab33/6442717/0c6d819e5e5e/1809-4406-aob-27-02-0104-gf01.jpg

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