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基于锝-99m、氟-18-氟代脱氧葡萄糖正电子发射断层显像及治疗性碘-131检查的核医学工作人员的职业辐射剂量

OCCUPATIONAL RADIATION DOSE TO NUCLEAR MEDICINE STAFF DUE TO TC99M, F18-FDG PET AND THERAPEUTIC I-131 BASED EXAMINATIONS.

作者信息

Fathy Mohamed, Khalil Magdy M, Elshemey Wael M, Mohamed Haitham S

机构信息

Department of Nuclear Medicine, Kasr Al-Ainy Center for Radiation Oncology and Nuclear Medicine, Faculty of Medicine, Cairo University, Egypt.

Department of Biophysics, Faculty of Science, Cairo University, Giza, Egypt.

出版信息

Radiat Prot Dosimetry. 2019 Dec 31;186(4):443-451. doi: 10.1093/rpd/ncz046.

DOI:10.1093/rpd/ncz046
PMID:30989207
Abstract

The aim was to track the exposure to radiation workers in six nuclear medicine examinations. A number of 180 patients were recruited and external exposure was measured. Patients had undergone cardiac stress and rest, bone scan, I-131 therapy, Gallium-67 and FDG PET/CT imaging. The average dose received due to cardiac stress and rest were 20.4 ± 5.0 and 16.0 ± 3.8 μSv per patient, respectively, whereas for bone scan, Ga-67, FDG and I-131 therapy, the average dose was 6.1 ± 2.5, 6.0 ± 1.4, 11.1 ± 2.2 and 4.1 ± 2.6 μSv per patient. The patient-to-staff dose coefficients were on average 0.051 ± 0.009, 0.042 ± 0.010, 0.034 ± 0.016, 0.039 ± 0.021, 0.052 ± 0.012, 0.094 ± 0.021 μSv m2/MBq h for stress, rest, bone, I-131, Ga-67 and FDG reported post-administration, respectively. Patient injection and setup for imaging represent a high percentage of the total dose received by staff. The information revealed is able to revise local measures, safety standards, and could help further in dose optimization and minimal exposure to occupationally exposed worker in nuclear medicine laboratories.

摘要

目的是追踪六类核医学检查中放射工作人员的辐射暴露情况。招募了180名患者并测量了其外部暴露情况。这些患者接受了心脏负荷与静息检查、骨扫描、I-131治疗、镓-67和氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG PET/CT)成像。每位患者因心脏负荷和静息检查所接受的平均剂量分别为20.4±5.0和16.0±3.8微希沃特,而对于骨扫描、镓-67、氟代脱氧葡萄糖和I-131治疗,每位患者的平均剂量分别为6.1±2.5、6.0±1.4、11.1±2.2和4.1±2.6微希沃特。给药后报告的患者与工作人员剂量系数,对于负荷、静息、骨、I-131、镓-67和氟代脱氧葡萄糖检查分别平均为0.051±0.009、0.042±0.010、0.034±0.016、0.039±0.021、0.052±0.012、0.094±0.021微希沃特·平方米/兆贝可勒尔·小时。患者注射及成像准备占工作人员所接受总剂量的很大比例。所披露的信息能够修订当地措施、安全标准,并有助于进一步优化剂量以及使核医学实验室中职业暴露工作人员的暴露降至最低。

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