Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C., Evin, Tehran, Iran.
Department of biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C., Evin, Tehran, Iran.
Nat Prod Res. 2020 Oct;34(20):2913-2918. doi: 10.1080/14786419.2019.1598988. Epub 2019 Apr 16.
Phytochemical investigation of the aerial parts of led to the isolation of a new oleane type triterpenoid ester (), together with six known compounds ), comprising one phenyl ethanoid ester, one glycosylated flavonoid, two triterpenoids, and two steroids. Their structures were elucidated by interpretation of their one-dimensional and two-dimensional NMR spectra and completed by the analysis of the HRESIMS data. Compounds and were evaluated for their cytotoxic feature against human breast adenocarcinoma cell line (MDA-MB231) and human prostate cancer cell line (DU145). However, they did not show positive effect (IC > 75µM).[Figure: see text].
从地上部分中分离得到一个新的齐墩果烷型三萜酯 ()，以及六个已知化合物 ()，包括一个苯乙醇酸酯、一个糖基化黄酮、两个三萜和两个甾体。通过一维和二维 NMR 光谱的解析，并结合 HRESIMS 数据分析，确定了它们的结构。对化合物 () 和 () 的细胞毒性特征进行了评估，针对人乳腺癌腺癌细胞系 (MDA-MB231) 和人前列腺癌细胞系 (DU145)。然而，它们没有表现出积极的效果 (IC > 75µM)。[图：见正文]。
