Center for Healthcare Delivery Science, Nemours Children's Health System/Alfred I. duPont Hospital for Children, 1600 Rockland Road, Wilmington, DE, 19803, USA.
Department of Pediatrics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
J Clin Psychol Med Settings. 2020 Mar;27(1):48-53. doi: 10.1007/s10880-019-09618-2.
This pilot study examined changes in cancer-related post-traumatic stress symptoms (PTSS) across time for siblings of children with cancer. Siblings (N = 32; aged 8-18) completed a measure of anxiety, the Child PTSD Symptom Scale (CPSS), and the PTSD section of the Structured Clinical Interview for DSM-IV-TR (SCID) at twelve (SD = .9) and eighteen months (SD = 1.3) post-diagnosis. Moderate-to-severe PTSS was reported by 12 siblings (38%) at T1 and 7 (22%) at T2. Cluster analysis of PTSS data revealed five patterns: Few symptoms, stable across time (31%, n = 10); Mild symptoms, decreasing across time (16%, n = 5); Mild, stable symptoms (28%, n = 9); Moderate/severe symptoms, decreasing across time but remaining moderate (19%, n = 6); and Moderate/severe, stable symptoms (6%, n = 2). SCID data and anxiety scores distinguished siblings in the final two clusters from those with more favorable PTSS levels/trajectories. Additional research with larger samples is needed to validate these trajectories and examine factors that distinguish siblings with consistently elevated cancer-related PTSS from those with mild or significantly improving symptoms.
本初步研究考察了癌症患儿的兄弟姐妹在时间上的癌症相关创伤后应激症状 (PTSS) 的变化。兄弟姐妹（N = 32；年龄 8-18 岁）在诊断后 12 个月（SD = 0.9）和 18 个月（SD = 1.3）时完成了焦虑量表、儿童 PTSD 症状量表 (CPSS) 和 DSM-IV-TR 结构临床访谈 PTSD 部分 (SCID) 的测量。12 名兄弟姐妹（38%）在 T1 时报告了中度至重度 PTSS，7 名（22%）在 T2 时报告了中度至重度 PTSS。PTSS 数据的聚类分析显示了五种模式：少数症状，随时间稳定（31%，n=10）；轻度症状，随时间减少（16%，n=5）；轻度、稳定的症状（28%，n=9）；中度/重度症状，随时间减少但仍保持中度（19%，n=6）；以及中度/重度，稳定的症状（6%，n=2）。SCID 数据和焦虑评分将最后两个聚类中的兄弟姐妹与那些具有更有利的 PTSD 水平/轨迹的兄弟姐妹区分开来。需要进一步开展具有更大样本量的研究来验证这些轨迹，并研究区分持续存在癌症相关 PTSD 水平较高的兄弟姐妹与轻度或明显改善症状的兄弟姐妹的因素。
