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苏丹东部卡什米埃尔盖尔巴地区人类克里米亚-刚果出血热病毒血清阳性率升高。

Elevated Human Crimean-Congo Hemorrhagic Fever Virus Seroprevalence in Khashm el Girba, Eastern Sudan.

机构信息

Institute for Virology, University Clinics and Medical Faculty, University of Leipzig, Leipzig, Germany.

Centre for Infectious Disease Diagnostics, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

出版信息

Am J Trop Med Hyg. 2019 Jun;100(6):1549-1551. doi: 10.4269/ajtmh.18-0977.

DOI:10.4269/ajtmh.18-0977
PMID:30994100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6553917/
Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease that can evolve into deadly hemorrhagic fever and that is endemic in many parts of Europe, Middle East, Central Asia, and Africa. Because of several reports about CCHF outbreaks in the south of Sudan during the last years, we examined in this study if unrecognized CCHF-V infections also occurred in the eastern and central parts of the country. The study examined the seroprevalence of CCHF virus infection in 464 sera from three regions of Sudan without previous reports of CCHF infection. The total CCHF virus seroprevalence was 2.6% (12 sera). The percentage was significantly elevated (7.5%) in sera from Khashm el Girba in eastern Sudan. The population in this area should be educated about the risk of disease transmission and how to avoid the infection. Health-care providers should be informed about the disease to identify possible cases and to prevent nosocomial transmission.

摘要

克里米亚-刚果出血热(CCHF)是一种蜱媒疾病,可发展为致命性出血热,在欧洲、中东、中亚和非洲的许多地区流行。由于近年来在苏丹南部有几起因克里米亚-刚果出血热爆发的报告,我们在这项研究中检查了在该国东部和中部是否也发生了未被识别的 CCHF-V 感染。该研究检查了来自苏丹三个地区的 464 份血清中 CCHF 病毒感染的血清流行率,这些地区以前没有 CCHF 感染的报告。CCHF 病毒总血清流行率为 2.6%(12 份血清)。在来自苏丹东部的哈沙梅尔吉尔巴的血清中,这一比例显著升高(7.5%)。该地区的人群应该接受有关疾病传播风险和避免感染的教育。卫生保健提供者应该了解该疾病,以识别可能的病例并防止医院内传播。

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