1 Department of Endocrinology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
2 Danish Diabetes Academy, Odense, Denmark.
Diabetes Technol Ther. 2019 May;21(5):295-302. doi: 10.1089/dia.2019.0014. Epub 2019 Apr 17.
The aim was to compare the accuracy of the Dexcom G4 Platinum continuous glucose monitor (CGM) sensor inserted on the upper arm and the abdomen in adults. Fourteen adults with type 1 diabetes wore two CGMs, one placed on the upper arm and one placed on the abdomen. Three in-clinic visits of 5 h with YSI (2300 STAT, Yellow Springs Instrument) measurements as comparator were performed. Each visit was followed by 4 days with seven-point self-monitoring of blood glucose (SMBG) in free-living conditions. Accuracy analyses on the paired CGM-YSI and CGM-SMBG measurements of the two CGM sensors were performed. Using YSI as comparator, the overall Mean Absolute Relative Difference (MARD) for the CGM was 12.3% and CGM was 12.0%. The percentage of the CGM measurements in zone A of Clarke error grid analysis for the CGM was 85.6% and CGM was 86.0%. The hypoglycemia sensitivity for the CGM and CGM was 69.3%. Using SMBG as comparator, the overall MARD for the CGM was 12.5% and CGM was 12.0%. The percentage of the CGM measurements in zone A for the CGM was 84.1% and the CGM was 85.0%. The hypoglycemia sensitivity for the CGM was 60.0% and the CGM was 71.1%. All the -values from the comparisons between the accuracy of CGM and CGM were >0.05. The accuracy of a Dexcom G4 Platinum CGM sensor placed on the upper arm was not different from the accuracy of the sensor placed on the abdomen in adults with type 1 diabetes.
目的在于比较德康 G4 白金连续血糖监测仪（CGM）传感器在上臂和腹部插入在成人中的准确性。14 名 1 型糖尿病成人佩戴两个 CGM，一个在上臂，一个在腹部。进行了三次门诊 5 小时的 YSI（2300 STAT，Yellow Springs Instrument）测量作为比较。每次就诊后，在自由生活条件下进行 4 天的七点自我血糖监测（SMBG）。对两个 CGM 传感器的配对 CGM-YSI 和 CGM-SMBG 测量进行了准确性分析。使用 YSI 作为比较，CGM 的总体平均绝对相对差异（MARD）为 12.3%，CGM 为 12.0%。CGM 分析 Clarke 误差网格分析中 A 区的 CGM 测量百分比为 85.6%，CGM 为 86.0%。CGM 和 CGM 的低血糖敏感性为 69.3%。使用 SMBG 作为比较，CGM 的总体 MARD 为 12.5%，CGM 为 12.0%。CGM 分析 Clarke 误差网格分析中 A 区的 CGM 测量百分比为 84.1%，CGM 为 85.0%。CGM 的低血糖敏感性为 60.0%，CGM 为 71.1%。CGM 和 CGM 之间准确性比较的所有 - 值均>0.05。在上臂放置德康 G4 白金 CGM 传感器的准确性与 1 型糖尿病成人腹部放置传感器的准确性没有差异。
