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常见的拇外翻治疗前足手术后持续使用阿片类药物。

New Persistent Opioid Use Following Common Forefoot Procedures for the Treatment of Hallux Valgus.

机构信息

Departments of Orthopaedic Surgery (F.T.F, T.D.G., P.G.T., and J.R.H.), Surgery (H.M.H. and J.F.W.), and Anesthesiology (C.M.B.), University of Michigan, Ann Arbor, Michigan.

出版信息

J Bone Joint Surg Am. 2019 Apr 17;101(8):722-729. doi: 10.2106/JBJS.18.00793.

Abstract

BACKGROUND

Orthopaedic surgeons are the fourth highest on the list of top prescribers of opioid analgesics by specialty and have a direct impact on opioid-related morbidity in the United States. Operative bunion correction is one of the most commonly performed elective foot surgical procedures in this country. We sought to determine the rate of new persistent opioid use following exposure to opioids after surgical treatment of hallux valgus (bunionectomy) and to identify associated risk factors.

METHODS

A nationwide U.S. insurance claims database, Truven Health MarketScan, was used to identify opioid-naïve patients who underwent surgical treatment of hallux valgus employing 3 common procedures from January 2010 to June 2015. The rate of new persistent opioid use (i.e., fulfillment of an opioid prescription between 91 and 180 days after the surgical procedure) among patients who filled a perioperative opioid prescription was then calculated. A logistic regression model was used to examine the relationship between new persistent use and risk factors, including surgical procedure, patient demographic characteristics, and patient comorbidities.

RESULTS

A total of 36,562 patients underwent surgical treatment of hallux valgus and filled a perioperative opioid prescription. The rate of new persistent opioid use among all patients who filled a perioperative opioid prescription was 6.2%. Patients who underwent treatment with a first metatarsal-cuneiform arthrodesis were more likely to have new persistent opioid use compared with the distal metatarsal osteotomy control group (adjusted odds ratio, 1.19 [95% confidence interval, 1.03 to 1.39]; p = 0.021). Factors independently associated with new persistent opioid use included prescribing patterns, coexisting mental health diagnoses, and certain pain disorders.

CONCLUSIONS

New persistent opioid use following surgical treatment of hallux valgus affects a substantial number of patients. Understanding factors associated with persistent opioid use can help clinicians to identify and counsel at-risk patients and to mitigate this public health crisis.

LEVEL OF EVIDENCE

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

骨科医生是按专业划分开具阿片类镇痛药处方的第四高群体,他们直接影响着美国与阿片类药物相关的发病率。在美国,手术矫正拇囊炎(拇外翻)是最常见的足部选择性手术之一。我们旨在确定接受拇囊炎(拇外翻)手术治疗后使用阿片类药物的患者中,新出现持续性阿片类药物使用的比例,并确定相关的风险因素。

方法

我们使用美国全国性的医疗保险索赔数据库 Truven Health MarketScan 来确定 2010 年 1 月至 2015 年 6 月期间接受 3 种常见手术治疗拇囊炎的阿片类药物初治患者。然后计算在接受围手术期阿片类药物处方的患者中,新出现持续性阿片类药物使用(即术后 91-180 天内开具阿片类药物处方)的比例。使用逻辑回归模型来检查新出现持续性使用与风险因素之间的关系,包括手术程序、患者人口统计学特征和患者合并症。

结果

共有 36562 例患者接受了拇囊炎的手术治疗,并开具了围手术期阿片类药物处方。在所有接受围手术期阿片类药物处方的患者中,新出现持续性阿片类药物使用的比例为 6.2%。与接受第一跖骨-楔骨关节融合术的对照组相比,接受跖骨远侧截骨术的患者更有可能出现新的持续性阿片类药物使用(调整后的优势比,1.19 [95%置信区间,1.03 至 1.39];p = 0.021)。与新出现持续性阿片类药物使用独立相关的因素包括处方模式、共存的心理健康诊断和某些疼痛障碍。

结论

拇囊炎手术后出现新的持续性阿片类药物使用会影响大量患者。了解与持续性阿片类药物使用相关的因素可以帮助临床医生识别和咨询高危患者,并减轻这一公共卫生危机。

证据等级

治疗性 IV 级。请参阅作者说明,以获取完整的证据等级描述。

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