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肝硬化中的肝血窦。一项形态计量学研究。

The sinusoids in cirrhosis. A morphometric study.

作者信息

Pesce C, Colacino R

出版信息

Virchows Arch A Pathol Anat Histopathol. 1986;410(3):217-9. doi: 10.1007/BF00710827.

DOI:10.1007/BF00710827
PMID:3099464
Abstract

The volume fraction of the sinusoids (Vv), the sinusoidal surface:total volume ratio (Sv), and the sinusoidal length:total volume ratio (Lv) were evaluated morphometrically in twelve biopsy specimens with cirrhosis and in eleven control specimens. The Sv, which is directly related to the radius of the sinusoids, was significantly (0.01 greater than P greater than 0.001) greater in the cirrhotic group than in the controls. In contrast, the Lv, which is directly related to the length of the sinusoids, and the Vv did not vary significantly in the same groups. These data support the concept that changes of the sinusoids do not contribute to portal hypertension in cirrhosis.

摘要

在12份肝硬化活检标本和11份对照标本中,对肝血窦的体积分数(Vv)、肝血窦表面积与总体积之比(Sv)以及肝血窦长度与总体积之比(Lv)进行了形态计量学评估。与肝血窦半径直接相关的Sv在肝硬化组中显著高于对照组(P值大于0.001且小于0.01)。相比之下,与肝血窦长度直接相关的Lv以及Vv在相同组中无显著差异。这些数据支持了肝血窦变化不会导致肝硬化门静脉高压这一观点。

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本文引用的文献

1
Correlation of intrahepatic pressure with collagen in the Disse space and hepatomegaly in humans and in the rat.人及大鼠肝内压力与狄氏间隙胶原蛋白及肝肿大的相关性
Gastroenterology. 1981 Mar;80(3):546-56.
2
The role of hepatocyte enlargement in hepatic pressure in cirrhotic and noncirrhotic alcoholic liver disease.肝细胞肿大在肝硬化和非肝硬化酒精性肝病肝内压力中的作用。
Hepatology. 1982 Sep-Oct;2(5):539-46. doi: 10.1002/hep.1840020505.
3
Perivenular fibrosis in alcoholic liver injury: ultrastructure and histologic progression.酒精性肝损伤中的肝静脉周围纤维化:超微结构与组织学进展
Gastroenterology. 1982 Oct;83(4):777-85.
4
Correlation between liver morphology and portal pressure in alcoholic liver disease.
Hepatology. 1984 Jul-Aug;4(4):699-703. doi: 10.1002/hep.1840040423.
5
The scarring of the liver acini (Cirrhosis). Tridimensional and microcirculatory considerations.肝腺泡的瘢痕形成(肝硬化)。三维及微循环方面的考量。
Virchows Arch A Pathol Anat Histopathol. 1983;402(2):107-37. doi: 10.1007/BF00695054.
6
A morphometric analysis of the hypertrophy of experimental liver cirrhosis.实验性肝硬化肝脏肥大的形态计量学分析
Virchows Arch A Pathol Anat Histopathol. 1983;400(2):173-86. doi: 10.1007/BF00585499.
7
Liver biopsy interpretation in hepatitis. Part I. Presentation of critical morphologic features used in diagnosis (glossary).肝炎的肝活检解读。第一部分。用于诊断的关键形态学特征介绍(术语表)。
Pathol Res Pract. 1983 Aug;178(1):2-19. doi: 10.1016/S0344-0338(83)80080-6.
8
Hepatic vascular changes in human and experimental cirrhosis.人类及实验性肝硬化中的肝血管变化
J Pathol Bacteriol. 1966 Oct;92(2):405-14. doi: 10.1002/path.1700920219.
9
The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization.肝硬化的形态学。由世界卫生组织赞助的一个工作组关于定义、命名和分类的建议。
J Clin Pathol. 1978 May;31(5):395-414. doi: 10.1136/jcp.31.5.395.
10
Pathologic aspects of cirrhosis. A review.肝硬化的病理学方面。综述。
Am J Pathol. 1977 Apr;87(1):228-64.