重症基孔肯雅热感染儿童的临床和实验室特征
Clinical and laboratory profiles of children with severe chikungunya infection.
作者信息
Beserra Francisca Lillyan Christyan Nunes, Oliveira Gustavo Mesquita, Marques Tino Miro Aurélio, Farias Luís Arthur Brasil Gadelha, Santos Janete Romão Dos, Daher Elizabeth De Francesco, Leite Robério Dias, Girão Evelyne Santana, Pires Neto Roberto da Justa
机构信息
Departamento de Saúde Comunitária, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
Departamento de Medicina Clínica, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
出版信息
Rev Soc Bras Med Trop. 2019 Apr 11;52:e20180232. doi: 10.1590/0037-8682-0232-2018.
INTRODUCTION
Chikungunya infection presents with distinct clinical features depending on the patient age group.
METHODS
Medical records of children with positive IgM for the chikungunya virus who were hospitalized in a pediatric ward in Fortaleza, Ceará, Brazil were analyzed.
RESULTS
Fourteen children with a median age of 4 months (36 days to 15 years) were included. All patients presented with fever persisting for an average of 5 days. The joints were involved in 6 (42.8%) children, and 8 (57.1%) children presented with bullous rash.
CONCLUSIONS
Systemic involvement and atypical clinical manifestations characterize severe forms of chikungunya infection in children.
引言
基孔肯雅热感染根据患者年龄组呈现出不同的临床特征。
方法
对在巴西塞阿拉州福塔莱萨的一家儿科病房住院的基孔肯雅病毒IgM检测呈阳性的儿童的病历进行分析。
结果
纳入了14名儿童，中位年龄为4个月（36天至15岁）。所有患者均出现发热，平均持续5天。6名（42.8%）儿童有关节受累，8名（57.1%）儿童出现大疱性皮疹。
结论
全身受累和非典型临床表现是儿童基孔肯雅热严重感染形式的特征。
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