Machado Soraia Goretti Machado Rocha, Quadros Thiago, Watanabe Yoshimi, Aquino Cecília F, Otoni Alba, Pinto Sérgio Wyton
MD, Specializing in Nephrology - São João de Deus Hospital, Divinópolis, Minas Gerais - Brasil.
MD, Nephrologist, MSc - University of Pernambuco - Brasil.
Rev Assoc Med Bras (1992). 2019 Mar;65(3):441-445. doi: 10.1590/1806-9282.65.3.441. Epub 2019 Apr 11.
We analyzed the distribution and frequency of glomerular diseases in patients biopsied between 1992 and 2016 in centers that make up the AMICEN (Minas Gerais Association of Nephrology Centers).
We analyzed the biopsy reports of patients from 9 AMICEN nephrology centers. We took note of their age, gender, ultrasound use, post-biopsy resting time, whether the kidney was native or a graft, number of glomeruli and indication for the biopsy. The kidney biopsy findings were broken down into four categories: glomerular and non-glomerular diseases, normal kidneys and insufficient material for analysis. Those patients diagnosed with glomerular diseases were further divided into having primary or secondary glomerular diseases.
We obtained 582 biopsy reports. The median age was 38 years (1 to 85). The number of glomeruli varied between 0 and 70 (median = 13.0). In total, 97.8% of the biopsies were ultrasound guided. The main indication was nephrotic syndrome (36.9%), followed by hematuria-proteinuria association (16.2%). Primary glomerular diseases proved to be the most frequent (75.3%), followed by secondary diseases (24.7%). Among the primary glomerular diseases, FSGS was found at a higher frequency (28.8%), while among the secondary diseases, SLE was the most prevalent (42.4%). Regarding prevalence findings, those for both primary and secondary diseases were similar to those found in the large Brazilian registries published thus far.
Glomerular disease registries are an important tool to identify the prevalence of such disease in regions of interest and can serve as an instrument to guide public policy decisions concerning the prevention of terminal kidney diseases.
我们分析了1992年至2016年间在组成AMICEN（米纳斯吉拉斯州肾脏病中心协会）的各中心接受活检的患者中肾小球疾病的分布情况及发病率。
我们分析了来自9个AMICEN肾脏病中心患者的活检报告。记录了他们的年龄、性别、是否使用超声、活检后休息时间、肾脏是自体肾还是移植肾、肾小球数量以及活检指征。肾脏活检结果分为四类：肾小球疾病和非肾小球疾病、正常肾脏以及分析材料不足。那些被诊断为肾小球疾病的患者进一步分为原发性或继发性肾小球疾病。
我们获得了582份活检报告。中位年龄为38岁（1至85岁）。肾小球数量在0至70之间（中位数 = 13.0）。总共有97.8%的活检是在超声引导下进行的。主要指征是肾病综合征（36.9%），其次是血尿 - 蛋白尿合并症（16.2%）。原发性肾小球疾病最为常见（75.3%），其次是继发性疾病（24.7%）。在原发性肾小球疾病中，局灶节段性肾小球硬化症的发病率较高（28.8%），而在继发性疾病中，系统性红斑狼疮最为普遍（42.4%）。关于患病率的研究结果，原发性和继发性疾病的患病率与迄今为止巴西大型登记处的研究结果相似。
肾小球疾病登记是确定感兴趣地区此类疾病患病率的重要工具，可作为指导有关预防终末期肾病的公共政策决策的手段。
