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肺移植术后伴严重并发症的肺康复:一例报告

Pulmonary rehabilitation after lung transplantation with severe complications: A case report.

作者信息

Jing Guo-Qiang, Li Jie, Sun Bing, Chu Huiwen, Li Haichao, Wang Xue, Tang Xiao

机构信息

Binzhou Medical University, Binzhou Medical University Hospital, Intensive Care Unit, Binzhou, Shandong, 256600, PR China.

Department of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University Medical Center, Chicago, IL. 60612, USA.

出版信息

Can J Respir Ther. 2017 Summer;53(3):45-47. Epub 2017 Aug 1.

PMID:30996633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6422215/
Abstract

This case study describes a 59-year-old male with a body mass index of 14.4 kg/m and a diagnosis of interstitial lung disease, pneumoconiosis, and severe pulmonary hypertension who received a bilateral lung transplant in a hospital in mainland China. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) was initiated before the lung transplant; in addition, an emergency thoracotomy was performed three hours afterwards due to uncontrolled bleeding. VA-ECMO was weaned 34 hours later, but weaning from the ventilator failed multiple times due to bilateral pneumothorax, weak neuromuscular drive, and muscle strength. A full, personalized rehabilitation program was initiated with the help of a respiratory therapy team and the physician, drawing on the American Thoracic Society/European Respiratory Society Statement on Pulmonary Rehabilitation. This included nutrition support, draining air from the chest pleural cavity, aggressive bronchial-hygiene therapy, a weaning plan, breathing and physical exercises, and psychological support. Eighty-one days after the tracheotomy, the patient was successfully weaned, decannulated, and discharged. A careful, ongoing evaluation and a personalized program assisted with weaning this difficult patient.

摘要

本病例研究描述了一名59岁男性,体重指数为14.4kg/m,诊断为间质性肺疾病、尘肺病和重度肺动脉高压,在中国内地一家医院接受了双肺移植。在肺移植前启动了静脉-动脉体外膜肺氧合(VA-ECMO);此外,由于出血无法控制,在三小时后进行了急诊开胸手术。34小时后VA-ECMO撤机,但由于双侧气胸、神经肌肉驱动和肌力较弱,多次尝试脱离呼吸机均失败。在呼吸治疗团队和医生的帮助下,根据美国胸科学会/欧洲呼吸学会关于肺康复的声明,启动了全面的个性化康复计划。这包括营养支持、胸腔引流、积极的支气管卫生治疗、撤机计划、呼吸和体育锻炼以及心理支持。气管切开术后81天,患者成功脱机、拔管并出院。仔细的持续评估和个性化计划有助于使这位困难患者成功脱机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/6422215/5995e5e9129a/CJRT-53-45-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/6422215/20a9abe1cf10/CJRT-53-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/6422215/5995e5e9129a/CJRT-53-45-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/6422215/20a9abe1cf10/CJRT-53-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eb7/6422215/5995e5e9129a/CJRT-53-45-g002.jpg

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本文引用的文献

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ICU Care Before and After Lung Transplantation.重症监护病房在肺移植前后的护理。
Chest. 2016 Aug;150(2):442-50. doi: 10.1016/j.chest.2016.02.656. Epub 2016 Mar 4.
2
Underweight and obesity increase the risk of mortality after lung transplantation: a systematic review and meta-analysis.体重过轻和肥胖会增加肺移植术后的死亡风险:一项系统评价和荟萃分析。
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Effect of high-frequency chest wall oscillation versus chest physiotherapy on lung function after lung transplant.高频胸壁振荡与胸部物理治疗对肺移植术后肺功能的影响。
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An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation.美国胸科学会/欧洲呼吸学会官方声明:肺康复的关键概念和进展。
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Effects of nutritional status and dietetic interventions on survival in Cystic Fibrosis patients before and after lung transplantation.营养状况和饮食干预对囊性纤维化患者肺移植前后生存率的影响。
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Low vitamin D levels are associated with increased rejection and infections after lung transplantation.维生素 D 水平低与肺移植后排斥反应和感染增加有关。
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