Maltsev Dmitrii S, Kulikov Alexei N, Chhablani Jay
Ophthalmic Surg Lasers Imaging Retina. 2019 Apr 1;50(4):e118-e124. doi: 10.3928/23258160-20190401-16.
To present clinical application of fluorescein angiography (FA)-free focal laser photocoagulation (FLP) of the leakage point in patients with central serous chorioretinopathy (CSC).
A prospective case series included 16 eyes of 16 patients with non-resolved CSC. The leakage point was identified with optical coherence tomography (OCT) as a small single pigment epithelium detachment (PED) localized in the upper half of the neurosensory detachment with an area of photoreceptor outer segments layer thinning above this PED. FLP was performed with the Navilas 532 system.
All patients achieved complete resolution of the subretinal fluid within a mean time of 6.5 ± 1.8 weeks. The mean best-corrected visual acuity statistically significantly increased from 0.08 ± 0.09 (20/25) at baseline to 0.0 ± 0.04 (20/20) at 2 months after FLP (P = .0005).
FA-free, OCT-guided navigated FLP is an effective and safe option to treat a significant number of patients with CSC. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e118-e124.].
介绍无荧光素血管造影（FA）的局灶性激光光凝术（FLP）在中心性浆液性脉络膜视网膜病变（CSC）患者渗漏点的临床应用。
一项前瞻性病例系列研究纳入了16例CSC未愈患者的16只眼。通过光学相干断层扫描（OCT）将渗漏点识别为位于神经感觉层脱离上半部分的单个小色素上皮脱离（PED），该PED上方的光感受器外段层区域变薄。使用Navilas 532系统进行FLP。
所有患者在平均6.5±1.8周的时间内视网膜下液完全吸收。平均最佳矫正视力从基线时的0.08±0.09（20/25）统计学显著提高到FLP后2个月时的0.0±0.04（20/20）（P = .0005）。
无FA、OCT引导的导航FLP是治疗大量CSC患者的一种有效且安全的选择。[《眼科手术、激光与影像学视网膜》。2019；50：e118 - e124。]
