Ophthalmic Surg Lasers Imaging Retina. 2020 Sep 1;51(9):512-520. doi: 10.3928/23258160-20200831-06.
A computational model has predicted parameters for using a navigated microsecond pulsing laser system to treat central serous chorioretinopathy (CSC).
A prospective, single-center, interventional case series was conducted for patients with acute CSC who were enrolled following screening and informed consent. Treatment involved laser pulse duration of 50 μs, 2.4% Duty Cycle, 100 μm spot size, and 10 ms pulse duration.
Average best-corrected visual acuity (decimal) of 12 patients improved from 0.86 ± 0.03 at baseline to 0.97 ± 0.01 at 3 months. Baseline central retinal thickness decreased from 452.58 μm ± 24.53 μm at baseline to 249.25 μm ± 2.92 μm at 3 months. Retinal sensitivity improved from 24.1 dB ± 1.09 dB at baseline to 28.98 dB ± 0.23 dB at 3 months. In all cases, subretinal fluid was resorbed.
The parameter sets derived from the computer model can be applied safely and effectively for CSC treatment using the navigated microsecond pulsing laser system. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:512-520.].
一个计算模型已经预测出使用导航微秒脉冲激光系统治疗中心性浆液性脉络膜视网膜病变（CSC）的参数。
一项前瞻性、单中心、干预性病例系列研究纳入了急性 CSC 患者，这些患者在经过筛选和知情同意后被纳入研究。治疗包括激光脉冲持续时间 50 μs、2.4%占空比、100 μm 光斑大小和 10 ms 脉冲持续时间。
12 名患者的平均最佳矫正视力（十进制）从基线时的 0.86 ± 0.03 提高到 3 个月时的 0.97 ± 0.01。基线中央视网膜厚度从基线时的 452.58 μm ± 24.53 μm 降低到 3 个月时的 249.25 μm ± 2.92 μm。视网膜敏感度从基线时的 24.1 dB ± 1.09 dB 提高到 3 个月时的 28.98 dB ± 0.23 dB。在所有情况下，视网膜下液均被吸收。
从计算机模型得出的参数集可以安全有效地应用于导航微秒脉冲激光系统治疗 CSC。[眼科手术激光成像视网膜。2020;51:512-520.]。
