Zhou Fen, Wang Cheng-Hu, Zhou Chen-Chen, Liu Sha, Yao Jin, Jiang Qin
Nanjing Medical University Affiliated Eye Hospital, Nanjing 290091, Jiangsu Province, China.
Int J Ophthalmol. 2024 Nov 18;17(11):2045-2051. doi: 10.18240/ijo.2024.11.10. eCollection 2024.
To compare the short-term effectiveness of intelligent navigated laser photocoagulation and 577-nm subthreshold micropulse laser (SML) treatment in patients with chronic central serous chorioretinopathy (cCSC).
This observational retrospective cohort study included 60 consecutive patients who underwent intelligent navigated laser photocoagulation (=30) or 577-nm SML treatment (=30) for cCSC between Jan. 2021 and Oct. 2022. During 3mo follow-up, all patients underwent assessments of best correct visual acuity (BCVA) and optical coherence tomography (OCT).
The operation of laser treatment was successful in all cases. At 1mo, BCVA improved significantly more in the intelligent navigated laser photocoagulation group compared to the SML group (<0.05). The change was not significantly different at 3mo (>0.05). Central macular thickness (CMT) in the intelligent navigated laser photocoagulation group was lower than in the SML group at 1mo (<0.05). The subfoveal choroidal thickness (SFCT) in two groups were all significantly improved at 3mo (all <0.05). The change between two groups was not significantly different at 1mo or at 3mo (>0.05).
Intelligent navigated laser photocoagulation is superior to SML for treating cCSC, leading to better improvements in vision and CMT for short term.
比较智能导航激光光凝术与577纳米阈下微脉冲激光(SML)治疗慢性中心性浆液性脉络膜视网膜病变(cCSC)患者的短期疗效。
这项观察性回顾性队列研究纳入了2021年1月至2022年10月期间连续60例接受智能导航激光光凝术(n = 30)或577纳米SML治疗(n = 30)的cCSC患者。在3个月的随访期间,所有患者均接受了最佳矫正视力(BCVA)和光学相干断层扫描(OCT)评估。
所有病例的激光治疗操作均成功。在1个月时,智能导航激光光凝术组的BCVA改善程度明显高于SML组(P<0.05)。在3个月时,差异无统计学意义(P>0.05)。智能导航激光光凝术组在1个月时的中心黄斑厚度(CMT)低于SML组(P<0.05)。两组的黄斑中心凹下脉络膜厚度(SFCT)在3个月时均显著改善(均P<0.05)。两组之间在1个月或3个月时的变化无显著差异(P>0.05)。
智能导航激光光凝术在治疗cCSC方面优于SML,在短期内能使视力和CMT得到更好的改善。