The University of Queensland Diamantina Institute, Brisbane, Australia; Transplant Research Program, Boston Children's Hospital, Boston, MA, United States of America.
Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia; Division of Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Cousins Center for Neuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, USA.
J Neuroimmunol. 2019 Jul 15;332:99-111. doi: 10.1016/j.jneuroim.2019.04.006. Epub 2019 Apr 11.
Neurotransmitters and neurochemicals can act on lymphocytes by binding to receptors expressed by lymphocytes. This review describes lymphocyte expression of receptors for a selection of neurotransmitters and neurochemicals, the anatomical locations where lymphocytes can interact with neurotransmitters, and the effects of the neurotransmitters on lymphocyte function. Implications for health and disease are also discussed.
神经递质和神经化学物质可以通过与淋巴细胞表达的受体结合来作用于淋巴细胞。本综述描述了淋巴细胞对一系列神经递质和神经化学物质的受体表达、淋巴细胞与神经递质相互作用的解剖位置，以及神经递质对淋巴细胞功能的影响。还讨论了它们对健康和疾病的影响。
