Glaser Allison M, Geisler William M, Ratliff Amy E, Xiao Li, Waites Ken B, Gaisa Michael
1 Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
2 Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Int J STD AIDS. 2019 Apr;30(5):512-514. doi: 10.1177/0956462418816757. Epub 2019 Jan 10.
Mycoplasma genitalium (MG) infection is a sexually transmitted infection that causes up to 25% of nongonococcal urethritis (NGU). MG strains carrying genetic markers of antimicrobial resistance that may affect treatment outcomes are increasingly recognized as a public health concern. We present two cases of persistent MG NGU with strains carrying both macrolide and quinolone resistance-associated mutations that were eradicated successfully by an extended course of minocycline.
生殖支原体（MG）感染是一种性传播感染，可导致高达25%的非淋菌性尿道炎（NGU）。携带可能影响治疗结果的抗菌药物耐药性基因标记的MG菌株日益被视为一个公共卫生问题。我们报告了两例持续性MG NGU病例，其菌株同时携带大环内酯类和喹诺酮类耐药相关突变，通过延长疗程的米诺环素成功根除。
