• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阿奇霉素、米诺环素、莫西沙星及大观霉素在中国广州一例持续性感染病例中治疗失败。

Azithromycin, minocycline, moxifloxacin and spectinomycin failure in a case with persistent infection in Guangzhou, China.

作者信息

Yang Ligang, Ke Wujian

机构信息

Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, China.

出版信息

Int J STD AIDS. 2020 Oct;31(11):1106-1109. doi: 10.1177/0956462420905269. Epub 2020 Aug 25.

DOI:10.1177/0956462420905269
PMID:32842908
Abstract

We report a case of -positive non-gonococcal urethritis who failed to respond to multiple different courses of antibiotics including azithromycin, minocycline, moxifloxacin and spectinomycin. Extracted DNA from urethral swabs obtained from the patient harbored mutations of 23S rRNA, and . Microbiological cure was eventually achieved by a 14-day course of doxycycline.

摘要

我们报告一例对阿奇霉素、米诺环素、莫西沙星和大观霉素等多种不同疗程抗生素治疗均无反应的淋病奈瑟菌阴性非淋菌性尿道炎病例。从该患者尿道拭子中提取的DNA存在23S rRNA突变,以及……最终通过14天的强力霉素疗程实现了微生物学治愈。

相似文献

1
Azithromycin, minocycline, moxifloxacin and spectinomycin failure in a case with persistent infection in Guangzhou, China.阿奇霉素、米诺环素、莫西沙星及大观霉素在中国广州一例持续性感染病例中治疗失败。
Int J STD AIDS. 2020 Oct;31(11):1106-1109. doi: 10.1177/0956462420905269. Epub 2020 Aug 25.
2
Failure of moxifloxacin treatment in Mycoplasma genitalium infections due to macrolide and fluoroquinolone resistance.由于大环内酯类和氟喹诺酮类耐药,莫西沙星治疗生殖支原体感染失败。
Int J STD AIDS. 2013 Oct;24(10):822-8. doi: 10.1177/0956462413502008. Epub 2013 Aug 29.
3
Azithromycin treatment failure in Mycoplasma genitalium-positive patients with nongonococcal urethritis is associated with induced macrolide resistance.阿奇霉素治疗解脲脲原体阳性的非淋菌性尿道炎患者失败与诱导产生大环内酯类耐药有关。
Clin Infect Dis. 2008 Dec 15;47(12):1546-53. doi: 10.1086/593188.
4
Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.耐莫昔沙星和敏感的支原体生殖器菌株中 ParC 和 GyrA 的突变。
PLoS One. 2018 Jun 8;13(6):e0198355. doi: 10.1371/journal.pone.0198355. eCollection 2018.
5
Remarkable increase in fluoroquinolone-resistant Mycoplasma genitalium in Japan.日本氟喹诺酮类药物耐药解脲支原体显著增加。
J Antimicrob Chemother. 2014 Sep;69(9):2376-82. doi: 10.1093/jac/dku164. Epub 2014 Jun 2.
6
Macrolide and fluoroquinolone associated mutations in Mycoplasma genitalium in a retrospective study of male and female patients seeking care at a STI Clinic in Guangzhou, China, 2016-2018.大环内酯类和氟喹诺酮类相关突变在 2016-2018 年中国广州性传播感染诊所就诊的男性和女性患者的生殖支原体中的回顾性研究。
BMC Infect Dis. 2020 Dec 11;20(1):950. doi: 10.1186/s12879-020-05659-3.
7
Emergence of Mycoplasma genitalium with clinically significant fluoroquinolone resistance conferred by amino acid changes both in GyrA and ParC in Japan.在日本,由于GyrA和ParC中的氨基酸变化,出现了具有临床显著氟喹诺酮耐药性的生殖支原体。
J Infect Chemother. 2017 Sep;23(9):648-650. doi: 10.1016/j.jiac.2017.03.008. Epub 2017 Apr 24.
8
Azithromycin and moxifloxacin resistance determinants in Mycoplasma genitalium in Lleida, Spain.西班牙莱里达地区生殖支原体中阿奇霉素和莫西沙星耐药决定因素。
Rev Esp Quimioter. 2024 Jun;37(3):270-273. doi: 10.37201/req/015.2024. Epub 2024 Apr 9.
9
Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance.阿奇霉素 1.5g 连用 5 天与单次 1g 剂量治疗尿道解脲支原体感染:对治疗结局和耐药性的影响。
Clin Infect Dis. 2017 Feb 1;64(3):250-256. doi: 10.1093/cid/ciw719. Epub 2016 Oct 24.
10
Macrolide resistance and azithromycin failure in a Mycoplasma genitalium-infected cohort and response of azithromycin failures to alternative antibiotic regimens.大环内酯类耐药和阿奇霉素治疗失败的支原体生殖器感染队列和阿奇霉素治疗失败对替代抗生素方案的反应。
Clin Infect Dis. 2015 Apr 15;60(8):1228-36. doi: 10.1093/cid/ciu1162. Epub 2014 Dec 23.

引用本文的文献

1
Effects of azithromycin on serum inflammatory factors and T lymphocyte subsets in patients with gynecological mycoplasma infection.阿奇霉素对妇科支原体感染患者血清炎症因子及T淋巴细胞亚群的影响
Pak J Med Sci. 2022 Nov-Dec;38(8):2296-2300. doi: 10.12669/pjms.38.8.6283.