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脊髓室管膜瘤——手术治疗与预后

Spinal Cord Ependymoma - Surgical Management and Outcome.

作者信息

Mohammed Wail, Farrell Michael, Bolger Ciaran

机构信息

Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland.

Department of Neuropathology, Beaumont Hospital, Dublin, Ireland.

出版信息

J Neurosci Rural Pract. 2019 Apr-Jun;10(2):316-320. doi: 10.4103/jnrp.jnrp_267_18.

Abstract

BACKGROUND

Ependymoma is a common primary neoplasm of the spinal cord and filum terminale. Patients with spinal ependymoma usually experience gradual symptoms due to slow progression of the tumor; thus, early diagnosis can be challenging to make.

OBJECTIVE

The objective of this study was to report 5 years' experience in treating spinal intramedullary ependymomas and to illustrate the advantage of aggressive complete resection whenever possible.

PATIENTS AND METHODS

Retrospective medical notes of all patients with spinal ependymoma treated surgically over a 5-year period between January 2003 and January 2008 were recorded. Clinical presentation, spinal level, extent of resection, and complications were recorded. A prolonged follow-up was documented.

RESULTS

There were 20 patients - 11 males, and nine females -included in this study. Their median age was 48 years (range 3-75 years). In 18 patients, total gross resection was achieved. Subtotal resection was only possible in one patient due to surgical difficulty. One patient underwent biopsy and referred for further surgery and subsequently had total resection.

CONCLUSIONS

Radical total resection is achievable in spinal ependymomas, with minimal resultant morbidity.

摘要

背景

室管膜瘤是脊髓和终丝常见的原发性肿瘤。脊髓室管膜瘤患者通常因肿瘤进展缓慢而出现逐渐加重的症状;因此,早期诊断具有挑战性。

目的

本研究的目的是报告5年治疗脊髓髓内室管膜瘤的经验,并说明尽可能积极进行全切除的优势。

患者和方法

记录2003年1月至2008年1月这5年间所有接受手术治疗的脊髓室管膜瘤患者的回顾性病历。记录临床表现、脊髓节段、切除范围和并发症。进行了长期随访。

结果

本研究纳入20例患者,其中男性11例,女性9例。他们的中位年龄为48岁(范围3 - 75岁)。18例患者实现了全切除。由于手术困难,仅1例患者进行了次全切除。1例患者接受了活检,随后转诊进一步手术并最终实现了全切除。

结论

脊髓室管膜瘤可实现根治性全切除,术后并发症最少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a506/6454966/98a975ea9170/JNRP-10-316-g001.jpg

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