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基于临床症状的颅内脑膜瘤早期诊断的可能性

[Possibilities of early diagnosis of intracranial meningioma based on clinical symptoms].

作者信息

Baumgartner C, Kollegger H, Wessely P

出版信息

Dtsch Med Wochenschr. 1987 Jan 30;112(5):165-9. doi: 10.1055/s-2008-1068023.

Abstract

In a retrospective study, 56 patients with intracranial meningiomas were investigated. The diagnosis was verified by computer tomography with subsequent selective cerebral angiography in all cases. At the time of admission, 62.5% of the patients had functional losses affecting the cranial nerves, 44% functional losses involving the long nerve tracts and 23.2% had cerebellar symptoms. Nonspecific clinical symptoms found comprised headaches in 61% of the patients; these were already present almost three and a half years before the final diagnosis. There was a marked organic psychological disorder in 50% of the patients which had already been present retrospectively for an average of 10 months. Cerebral convulsive attacks were present in 27% of the patients with partial convulsions (mainly of the "temporal lobe type") which had already been present for an average of 40 months before diagnosis; in the general tonic-clonic convulsions, the diagnosis was already made an average of six weeks after the first attack. These data show that nonspecific symptoms such as headaches, organic psychological disorders and cerebral convulsions may be early indicators for the presence of an intracranial space occupation and should be investigated further without delay.

摘要

在一项回顾性研究中,对56例颅内脑膜瘤患者进行了调查。所有病例均通过计算机断层扫描并随后进行选择性脑血管造影来确诊。入院时,62.5%的患者存在影响颅神经的功能丧失,44%的患者存在涉及长神经束的功能丧失,23.2%的患者有小脑症状。发现的非特异性临床症状包括61%的患者有头痛;这些头痛在最终诊断前近三年半就已出现。50%的患者存在明显的器质性心理障碍,回顾性来看,这种障碍平均已存在10个月。27%的患者出现脑部惊厥发作,其中部分惊厥(主要为“颞叶型”)在诊断前平均已出现40个月;在全身强直阵挛性惊厥中,首次发作后平均六周就已确诊。这些数据表明,头痛、器质性心理障碍和脑部惊厥等非特异性症状可能是颅内占位性病变存在的早期指标,应立即进一步调查。

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