Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Cell Chem Biol. 2019 Apr 18;26(4):465-467. doi: 10.1016/j.chembiol.2019.04.005.
Ubiquinone (UQ) is a conserved polyprenylated lipid essential to cellular respiration. Two papers, one in this issue of Cell Chemical Biology (Hajj Chehade et al., 2019) and another in Molecular Cell (Lohman et al., 2019), identify lipid-binding proteins that play crucial roles in chaperoning UQ-intermediates.
泛醌(UQ)是一种保守的多聚异戊二烯脂质,对细胞呼吸至关重要。本期《细胞化学生物学》(Hajj Chehade 等人,2019)和《分子细胞》(Lohman 等人,2019)上的两篇论文都鉴定了脂质结合蛋白,这些蛋白在泛醌中间体的伴侣蛋白中发挥着关键作用。