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二叶式主动脉瓣在急性 A 型主动脉夹层手术后的意义。

The significance of bicuspid aortic valve after surgery for acute type A aortic dissection.

机构信息

Tampere University Heart Hospital and Tampere University, Tampere, Finland.

Karolinska University Hospital, Stockholm, Sweden.

出版信息

J Thorac Cardiovasc Surg. 2020 Mar;159(3):760-767.e3. doi: 10.1016/j.jtcvs.2019.03.012. Epub 2019 Mar 21.

DOI:10.1016/j.jtcvs.2019.03.012
PMID:31005301
Abstract

OBJECTIVE

Decision-making concerning the extent of the repair of acute type A aortic dissection (ATAAD) includes functional and anatomical assessment of the aortic valve. We hypothesized that bicuspid aortic valve (BAV) does not impact outcome after surgery for ATAAD. We therefore evaluated the outcome after ATAAD surgery in relation to the presence of BAV, acute aortic regurgitation (AR), and surgical approach, using the Nordic Consortium for Acute Type A Aortic Dissection database.

METHODS

Eight participating Nordic centers collected data from 1122 patients undergoing ATAAD surgery during the years 2005 to 2014. Early complications, reoperations and survival were compared between patients with BAV and tricuspid aortic valves (TAV) before and after propensity score matching for sex, age, AR, organ malperfusion, hemodynamic instability, and site of the tear. Mean follow-up (range) for patients with TAV and BAV was 3.1 years (0-10.4 years) and 3.2 years (0-9.0 years), respectively.

RESULTS

Altogether, 65 (5.8%) of the patients had BAV. Root replacement was more frequently performed in the BAV as compared with the TAV group (60% vs 23%, P < .001). Survival, however, did not differ significantly between patients with BAV or TAV, either before (P = .230) or after propensity score-matching (P = .812). Even so, in cohort as a whole, patients presenting with AR had less favorable survival.

CONCLUSIONS

Early and mid-term survival did not differ significantly between patients with BAV and TAV.

摘要

目的

急性 A 型主动脉夹层(ATAAD)修复范围的决策包括主动脉瓣的功能和解剖评估。我们假设二叶式主动脉瓣(BAV)不会影响 ATAAD 手术后的结果。因此,我们使用北欧急性 A 型主动脉夹层数据库评估了与 BAV、急性主动脉瓣反流(AR)和手术入路相关的 ATAAD 手术后的结果。

方法

8 个参与的北欧中心从 2005 年至 2014 年期间接受 ATAAD 手术的 1122 名患者中收集数据。在进行性别、年龄、AR、器官灌注不良、血流动力学不稳定和撕裂部位的倾向评分匹配后,比较了 BAV 和三尖瓣主动脉瓣(TAV)患者的早期并发症、再次手术和存活率。TAV 和 BAV 患者的平均随访时间(范围)分别为 3.1 年(0-10.4 年)和 3.2 年(0-9.0 年)。

结果

共有 65 名(5.8%)患者患有 BAV。与 TAV 组相比,BAV 组更常进行根部置换(60%比 23%,P<.001)。然而,BAV 或 TAV 患者的生存率在术前(P=.230)或倾向评分匹配后(P=.812)均无显著差异。即便如此,在整个队列中,出现 AR 的患者生存率较低。

结论

BAV 和 TAV 患者的早期和中期生存率无显著差异。

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