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[采用血浆置换缓解华氏巨球蛋白血症高黏滞综合征的眼部并发症]

[Alleviation of ocular complications of the hyperviscosity syndrome in Waldenström's macroglobulinemia using plasma exchange].

作者信息

Malecaze F, Mathis A, Gonzales C, Lloveras J J, Goudable C, Arlet P, Bec P

出版信息

J Fr Ophtalmol. 1986;9(5):367-71.

PMID:3100607
Abstract

Two patients presenting ocular complications of hyperviscosity syndrome in Waldenström's macroglobulinemia have been treated by plasmapheresis after inefficiency of immunosuppressive therapy. Plasma exchange seems an useful treatment as shown by clinic and angiographic improvement. In each case improvement of retinopathy was correlated with decrease of serum IgM level and blood viscosity measured by isotopic method. Fluorescein angiography, easily repeated, seems a very good method for following hyperviscosity syndrome in Waldenström's macroglobulinemia.

摘要

两名患有华氏巨球蛋白血症高黏滞综合征眼部并发症的患者在免疫抑制治疗无效后接受了血浆置换治疗。如临床和血管造影改善所示,血浆置换似乎是一种有效的治疗方法。在每例患者中,视网膜病变的改善与血清IgM水平的降低以及通过同位素法测量的血液黏度降低相关。荧光素血管造影易于重复,似乎是监测华氏巨球蛋白血症高黏滞综合征的一种非常好的方法。

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