Yenigun A, Degirmenci N, Goktas S S, Dogan R, Ozturan O
Department of Otorhinolaryngology,Faculty of Medicine,Bezmialem Vakif University,Istanbul,Turkey.
J Laryngol Otol. 2019 May;133(5):376-379. doi: 10.1017/S0022215119000768. Epub 2019 Apr 22.
This study investigated the relationship between disease severity and taste and smell functions in patients with obstructive sleep apnoea syndrome.
A total of 65 patients with recurrent upper airway obstruction during sleep were included. Participants were divided into four groups according to apnoea-hypopnoea index, obtained on polysomnography. Smell and taste tests were performed on these patients.
A significant difference was observed between the smell thresholds of the groups for the identification test (p = 0.016). In the taste test, significant differences were observed between the groups in terms of sweet, sour, salty and bitter taste test thresholds (p = 0.029, p = 0.0005, p = 0.001 and p = 0.017, respectively).
As sleep apnoea severity increased (according to the apnoea-hypopnoea index) in obstructive sleep apnoea syndrome patients, the taste and smell thresholds decreased due to the effect of neuropathy and inflammation in the upper respiratory tract.
本研究调查阻塞性睡眠呼吸暂停综合征患者疾病严重程度与味觉和嗅觉功能之间的关系。
共纳入65例睡眠期间反复出现上呼吸道阻塞的患者。根据多导睡眠图获得的呼吸暂停低通气指数将参与者分为四组。对这些患者进行嗅觉和味觉测试。
在识别测试中，各组的嗅觉阈值之间观察到显著差异（p = 0.016）。在味觉测试中，各组在甜味、酸味、咸味和苦味测试阈值方面观察到显著差异（分别为p = 0.029、p = 0.0005、p = 0.001和p = 0.017）。
在阻塞性睡眠呼吸暂停综合征患者中，随着睡眠呼吸暂停严重程度增加（根据呼吸暂停低通气指数），由于上呼吸道神经病变和炎症的影响，味觉和嗅觉阈值降低。
