Schmidt-Kastner R, Ophoff B G, Hossmann K A
J Neurol. 1986 Nov;233(6):367-9. doi: 10.1007/BF00313924.
The cerebrovascular CO2 reactivity was examined after 6 h, 1, 2, and 3 days and 1 year following 1 h complete brain ischaemia in the cat. After 6 h recirculation, the CO2 reactivity was completely suppressed although major EEG activity had recovered. After 2 days, CO2 reactivity began to reappear, but even after 1 year restitution was not complete. The prolonged (though partly reversible) attenuation of CO2 responsiveness suggests that ischaemia is followed by a long-lasting state of haemodynamic imbalance, which may be responsible for the slow progress of post-ischaemic recovery processes.
在猫脑缺血1小时后，于6小时、1天、2天、3天及1年时检测脑血管二氧化碳反应性。再灌注6小时后，尽管主要脑电图活动已恢复，但二氧化碳反应性完全受到抑制。2天后，二氧化碳反应性开始重新出现，但即使在1年后仍未完全恢复。二氧化碳反应性的延长（尽管部分可逆）减弱表明，缺血后会出现长期的血流动力学失衡状态，这可能是缺血后恢复过程进展缓慢的原因。
