多灶性成人横纹肌瘤累及软腭的独特表现——病例报告及文献复习

Unique manifestation of a multifocal adult rhabdomyoma involving the soft palate-case report and review of literature.

作者信息

Dau Michael, Kraeft Stine-Kathrein, Kämmerer Peer Wolfgang

机构信息

Department of Oral, Maxillofacial and Plastic Surgery, University Medical Center Rostock, Rostock, Germany.

Department of Pathology, Rostock University, Rostock, Germany.

出版信息

J Surg Case Rep. 2019 Apr 16;2019(4):rjz116. doi: 10.1093/jscr/rjz116. eCollection 2019 Apr.

DOI:10.1093/jscr/rjz116

PMID:31007892

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6465952/

Abstract

Extracardiac adult rhabdomyoma is a rare benign tumor, which mainly occurs in the head and neck region and originates from striated muscle tissue. We report a 64-year-old male with simultaneous diagnosis of three adult rhabdomyomas including the soft palate and performed a review the literature on multifocal adult rhabdomyoma (mARM). Including the present case, 27 mARM with a range of 2-7 lesions per patient were collected. Mean age at diagnosis was 65 years with a male (23) to female (4) ratio of 5.75:1. Common localizations were parapharyngeal space (35%), larynx (14%), submandibular (13%), paratracheal region (14%), tongue (10%), floor of mouth (9%), neck (3%) and soft palate (2%). In accordance to this review, this the first case of mARM with involvement of the soft palate.

摘要

心脏外成人横纹肌瘤是一种罕见的良性肿瘤，主要发生在头颈部，起源于横纹肌组织。我们报告了一名64岁男性，同时诊断出包括软腭在内的三处成人横纹肌瘤，并对多灶性成人横纹肌瘤（mARM）的文献进行了综述。包括本病例在内，共收集了27例mARM，每位患者的病灶数为2至7个。诊断时的平均年龄为65岁，男性（23例）与女性（4例）的比例为5.75:1。常见的发病部位为咽旁间隙（35%）、喉（14%）、下颌下（13%）、气管旁区域（14%）、舌（10%）、口底（9%）、颈部（3%）和软腭（2%）。根据本综述，这是首例累及软腭的mARM。