de Trey Lorraine A, Schmid Stephan, Huber Gerhard F
Department of Otolaryngology, Head and Neck Surgery, University Hospital Zurich, Frauenklinikstraße 24, 8091 Zurich, Switzerland.
Case Rep Otolaryngol. 2013;2013:758416. doi: 10.1155/2013/758416. Epub 2013 Jun 13.
Background. Adult rhabdomyoma is a rare benign tumour with the differentiation of striated muscle tissue, which mainly occurs in the head and neck region. Twenty-six cases of multifocal adult rhabdomyoma are documented in the literature. Method. We report a 55-year-old male with simultaneous diagnosis of 7 adult rhabdomyomas and review the literature of multifocal adult rhabdomyoma. Result. Review of the literature revealed 26 cases of multifocal adult rhabdomyoma, of which only 7 presented with more than 2 lesions. Mean age at diagnosis was 65 years with a male to female ratio of 5.5 : 1. Common localizations were the parapharyngeal space (36%), larynx (15%), submandibular (14%), paratracheal region (12%), tongue (11%), and floor of mouth (9%). Besides the known radiological features of adult rhabdomyoma, our case showed FDG-uptake in (18) F-FDG PET/CT. Conclusion. This is the first case of multifocal adult rhabdomyoma published, with as many as 7 simultaneous adult rhabdomyomas of the head and neck.
背景。成人横纹肌瘤是一种罕见的具有横纹肌组织分化的良性肿瘤，主要发生在头颈部区域。文献记载了26例多灶性成人横纹肌瘤病例。方法。我们报告了一名55岁男性，同时诊断出7个成人横纹肌瘤，并回顾了多灶性成人横纹肌瘤的文献。结果。文献回顾显示有26例多灶性成人横纹肌瘤病例，其中只有7例出现2个以上病灶。诊断时的平均年龄为65岁，男女比例为5.5∶1。常见的发病部位为咽旁间隙（36%）、喉（15%）、下颌下（14%）、气管旁区域（12%）、舌（11%）和口底（9%）。除了成人横纹肌瘤已知的影像学特征外，我们的病例在（18）F-FDG PET/CT中显示有FDG摄取。结论。这是首例发表的多灶性成人横纹肌瘤病例，同时存在多达7个头颈部成人横纹肌瘤。
