Department of Psychiatry, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels.
Toxicological Center, Antwerp University, Antwerp, Belgium.
Curr Opin Psychiatry. 2019 Jul;32(4):300-306. doi: 10.1097/YCO.0000000000000513.
Attention-deficit and hyperactivity disorder (ADHD) often presents with comorbid substance use disorders (SUD). Due to similarities in key symptoms of both disorders and suboptimal efficacy of the available treatments, clinicians are faced with difficulties in the diagnosis and treatment of these patients with both disorders. This review addresses recent publications between 2017 and 2019 on the etiology, prevalence, diagnosis and treatment of co-occurring ADHD and SUD.
ADHD is diagnosed in 15-20% of SUD patients, mostly as ADHD with combined (hyperactive/inattentive) presentation. Even during active substance use, screening with the Adult ADHD Self-Report Scale (ASRS) is useful to address whether further diagnostic evaluation is needed. After SUD treatment, the diagnosis of ADHD generally remains stable, but ADHD subtype presentations are not. Some evidence supports pharmacological treatment with long-acting stimulants in higher than usual dosages. Studies on psychological treatment remain scarce, but there are some promising findings on integrated cognitive behaviour therapy.
Diagnosis and treatment of patients with comorbid ADHD and SUD remain challenging. As ADHD presentations can change during active treatment, an active follow-up is warranted to provide treatment to the individuals' personal strengths and weaknesses.
注意力缺陷多动障碍(ADHD)常伴有合并物质使用障碍(SUD)。由于两种疾病的主要症状相似,且现有治疗方法的疗效欠佳,临床医生在诊断和治疗同时患有这两种疾病的患者时面临困难。这篇综述讨论了 2017 年至 2019 年间关于共患 ADHD 和 SUD 的病因、患病率、诊断和治疗的最新文献。
ADHD 在 SUD 患者中诊断率为 15-20%,主要表现为 ADHD 合并(多动/注意力不集中)。即使在物质使用活跃期间,使用成人 ADHD 自评量表(ASRS)进行筛查也有助于确定是否需要进一步诊断评估。在 SUD 治疗后,ADHD 的诊断通常保持稳定,但 ADHD 亚型的表现并不稳定。一些证据支持使用长效兴奋剂以高于常规剂量进行药物治疗。有关心理治疗的研究仍然很少,但综合认知行为疗法有一些有希望的发现。
共患 ADHD 和 SUD 的患者的诊断和治疗仍然具有挑战性。由于 ADHD 的表现可能在积极治疗期间发生变化,因此需要进行积极的随访,以便根据个人的优势和劣势为其提供治疗。