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[放射性免疫及免疫法对放疗及甲状腺切除术后毒性甲状腺肿缓解情况的随访]

[Radioimmunological and immunological follow-up of toxic goiter remission following radiotherapy and thyroidectomy].

作者信息

Ametov A S, Livshits A Kh, Oleĭnik E K

出版信息

Med Radiol (Mosk). 1987 Feb;32(2):38-41.

PMID:3100903
Abstract

The paper is concerned with a multimodality approach to the assessment of clinical remission in 42 patients after radical therapy of toxic goiter. T4, T3, sigma TSH, delta TSH were determined in the thyrotropin releasing hormone stimulation test (TRH-test); some immunological indices (RFCc, RFCn, RFC1, a stimulation index [SI] LBTR, a migration index [MI] in the LMIT and serum immunoglobulins) were also investigated. The abnormal TRH-test was revealed in 2/3 of the patients (the hypo-TRH-test in 10 and the hyper-TRH-test in 11). A conclusion was made of the appropriateness of the multimodality approach to the assessment of toxic goiter remission after therapy.

摘要

本文探讨了一种多模态方法,用于评估42例毒性甲状腺肿根治性治疗后患者的临床缓解情况。在促甲状腺激素释放激素刺激试验(TRH试验)中测定了T4、T3、总促甲状腺激素(sigma TSH)、促甲状腺激素变化值(delta TSH);还研究了一些免疫指标(玫瑰花结形成细胞计数(RFCc)、玫瑰花结形成细胞绝对值(RFCn)、玫瑰花结形成细胞百分率(RFC1)、淋巴细胞转化试验刺激指数(SI)LBTR、淋巴细胞移动抑制试验迁移指数(MI)以及血清免疫球蛋白)。2/3的患者TRH试验异常(10例为TRH试验低下,11例为TRH试验亢进)。得出结论,多模态方法适用于评估治疗后毒性甲状腺肿的缓解情况。

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