从 亚种的全植物中分离得到的三种新的愈创木烷型倍半萜糖苷。
Three new muurolane-type sesquiterpene glycosides from the whole plants of subsp. .
机构信息
Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Graduate University of Science and Technology, VAST, Hanoi, Vietnam.
出版信息
Nat Prod Res. 2020 Oct;34(20):2964-2970. doi: 10.1080/14786419.2019.1602831. Epub 2019 Apr 22.
Three new muurolane type sesquiterpene glycosides, named balanoindicosides A - C (-), were isolated from the whole plant of subsp using various chromatographic methods. Their structures were determined by extensive analysis of HR-ESI-MS and NMR spectroscopy. The stereochemistry of muurolane sesquiterpene backbone was demonstrated by NOESY analysis. Configuration of C-12 in compounds and could be distinguished by chemical shift value of C-14. Compounds - exhibited weak cytotoxic activity towards HepG-2, HL-60, LU-1, and MCF-7 cell lines.
从巴戟天的全株植物中采用各种色谱方法分离得到了 3 种新的愈创木烷型倍半萜糖苷，命名为巴洛因迪昔斯苷 A - C(-)。通过高分辨电喷雾电离质谱和核磁共振波谱的广泛分析确定了它们的结构。通过 NOESY 分析证明了愈创木烷型倍半萜骨架的立体化学。化合物 和 的 C-12 构型可以通过 C-14 的化学位移值来区分。化合物 - 对 HepG-2、HL-60、LU-1 和 MCF-7 细胞系表现出较弱的细胞毒性活性。
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