Fiorillo Luca, De Stefano Rosa, Cervino Gabriele, Crimi Salvatore, Bianchi Alberto, Campagna Paola, Herford Alan Scott, Laino Luigi, Cicciù Marco
Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina, Italy.
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", 80121 Naples, Italy.
Biomedicines. 2019 Apr 20;7(2):33. doi: 10.3390/biomedicines7020033.
Haemophiliacs are hereditary coagulopathies whose basic anomaly consists of the quantitative or qualitative alteration of one or more plasma proteins in the coagulation system. The objective of this review is to analyse all risk factors, predispositions and alterations to the oral-maxillofacial district in patients with haemophilia. The broader assessment also includes the psychological aspects that could affect the treatment and maintenance of oral conditions. The study takes into consideration all the works in the literature in the last 10 years. Works that present oral, dental and psychological changes in haemophilia patients have been combined. A total of 16 studies were analysed carefully evaluating and explaining all the alterations and risk factors that this disease provides. The aim of the review is to report all the anomalies reported in the literature for these patients, and to direct and update the clinician in the treatment of haemophilia patients.
血友病是一种遗传性凝血障碍疾病,其基本异常表现为凝血系统中一种或多种血浆蛋白的数量或质量改变。本综述的目的是分析血友病患者口腔颌面部区域的所有危险因素、易患因素和改变情况。更广泛的评估还包括可能影响口腔状况治疗和维持的心理因素。该研究考虑了过去10年文献中的所有研究成果。将呈现血友病患者口腔、牙齿和心理变化的研究进行了汇总。共仔细分析了16项研究,评估并解释了该疾病所带来的所有改变和危险因素。本综述的目的是报告文献中所报道的这些患者的所有异常情况,并指导临床医生对血友病患者的治疗及进行知识更新。