螺旋霉素与红霉素对挪威细菌分离株的体外活性比较
The comparative in vitro activity of spiramycin and erythromycin against Norwegian bacterial isolates.
作者信息
Dibb W L, Ragnhildstveit E
出版信息
NIPH Ann. 1986 Dec;9(2):61-3.
PMID:3101004
Abstract
The in vitro activity of spiramycin and erythromycin has been determined by an agar diffusion method against relevant clinical isolates. Generally, erythromycin was more active than spiramycin on a weight-for-weight basis. Spiramycin showed only moderate activity against Haemophilus influenzae and Streptococcus pyogenes. Gonococci were sensitive in vitro to both agents. Many erythromycin-resistant staphylococci were sensitive to spiramycin.
摘要
已通过琼脂扩散法测定了螺旋霉素和红霉素对相关临床分离株的体外活性。一般来说，按重量计算，红霉素比螺旋霉素活性更强。螺旋霉素对流感嗜血杆菌和化脓性链球菌仅表现出中等活性。淋球菌在体外对这两种药物均敏感。许多耐红霉素的葡萄球菌对螺旋霉素敏感。
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