Stone L S, Lisberger S G
Neurosci Lett. 1986 Dec 12;72(2):163-8. doi: 10.1016/0304-3940(86)90073-x.
The activity of cerebellar Purkinje cells was monitored in alert monkeys during visually guided smooth pursuit eye movements. The climbing fiber input evokes 'complex-spikes' which show increased firing during the contralateral phase of sinusoidal pursuit. 'Complex-spike triggered averaging' revealed that the increased firing is a visual response to the retina slip which results from inaccurate tracking. The complex-spikes in turn cause a transient reduction in the simple-spike pursuit command signal that emanates from the flocculus and this may contribute to the corrective eye movement. We postulate that the detection (and possibly the correction) of small errors in motor performance may be a general function of climbing fiber inputs to the cerebellum.
在警觉的猴子进行视觉引导的平稳跟踪眼球运动期间，对小脑浦肯野细胞的活动进行了监测。攀缘纤维输入引发“复合峰”，在正弦跟踪的对侧相位期间，复合峰的放电增加。“复合峰触发平均法”表明，放电增加是对因跟踪不准确而导致的视网膜滑动的视觉反应。复合峰继而会使从小脑绒球发出的简单峰跟踪指令信号出现短暂减少，这可能有助于产生矫正性眼球运动。我们推测，对运动表现中的小误差进行检测（可能还有校正）可能是小脑攀缘纤维输入的一项普遍功能。
