使用口服避孕药的女性和正常女性中优球蛋白纤溶活性的日间增加以及内源性纤溶活性的产生。
The diurnal increase in euglobulin fibrinolytic activity in women using oral contraceptives and in normal women, and the generation of intrinsic fibrinolytic activity.
作者信息
Jespersen J
出版信息
Thromb Haemost. 1986 Oct 21;56(2):183-8.
PMID:3101221
Abstract
The diurnal fluctuations in plasma euglobulin fibrinolytic activity in women on oral contraceptives and in normal women showed similar patterns of increase. Following inactivation of inhibitors by flufenamate the individual increases and the evening levels did not differ. The diurnal increase was related to an increase in extrinsic (tissue-type) plasminogen activator (t-PA) activity, which contributes little to the total activity of the euglobulin fraction but induces an activation of the intrinsic system.
摘要
口服避孕药的女性和正常女性血浆优球蛋白纤维蛋白溶解活性的昼夜波动呈现出相似的升高模式。在用氟灭酸使抑制剂失活后，个体的升高幅度以及晚间水平并无差异。昼夜升高与外源性（组织型）纤溶酶原激活物（t-PA）活性的增加有关，t-PA对优球蛋白部分的总活性贡献不大，但会诱导内源性系统的激活。
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