Donaldson L E, Ward D N
Vet Rec. 1986;119(25-26):625-6.
Equivalent doses of follicle stimulating hormone (FSH) produced the same number of embryos and ova from a single flush irrespective of the luteinising hormone (LH) content of the superovulating drug (P less than 0.108). As the LH content of the FSH increased, the proportion of transferable embryos decreased (P less than 0.001) because the proportion fertilised decreased (P less than 0.001) and the degeneration rate of the fertilised embryos increased (P less than 0.002). FSH-W free from detectable luteinising hormone produced 8.8 embryos per flush of which 5.7 were transferable, representing 7.6 fertilised embryos of which 21 per cent had degenerated. The addition of a very small quantity of LH (FSH/LH ratio more than 500) resulted in 5.8 transferable embryos from a total of 10.6, of which 9.0 had been fertilised and 34 per cent of those fertilised had degenerated. Commercial FSH-P (FSH/LH less than 100) produced 3.3 transferable embryos from a total of 8.1, of which six had been fertilised and 39 per cent of those fertilised had degenerated. The luteinising hormone content of FSH-P has to be controlled and limited for optimum superovulation in cattle.
不论促排卵药物中黄体生成素（LH）的含量如何，同等剂量的促卵泡激素（FSH）单次冲卵所产生的胚胎和卵子数量相同（P＜0.108）。随着FSH中LH含量的增加，可移植胚胎的比例下降（P＜0.001），这是因为受精比例下降（P＜0.001）且受精胚胎的退化率上升（P＜0.002）。未检测到黄体生成素的无LH的FSH每次冲卵产生8.8个胚胎，其中5.7个可移植，即7.6个受精胚胎，其中21%发生退化。添加极少量的LH（FSH/LH比值大于500）后，10.6个胚胎中共有5.8个可移植，其中9.0个已受精，已受精胚胎中有34%发生退化。市售的FSH-P（FSH/LH小于100）在总共8.1个胚胎中产生3.3个可移植胚胎，其中6个已受精，已受精胚胎中有39%发生退化。为使牛达到最佳超排卵效果，必须控制和限制FSH-P中的黄体生成素含量。
