使用空气作为阴性对比剂的计算机断层扫描在山羊死后的影像学研究。
Postmortem imaging in goats using computed tomography with air as a negative contrast agent.
机构信息
Department of Small Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.
Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.
出版信息
PLoS One. 2019 Apr 23;14(4):e0215758. doi: 10.1371/journal.pone.0215758. eCollection 2019.
PURPOSE
Evaluation of the usefulness of air as a negative contrast medium of blood vessels in goats in post mortem computed tomography (PMCT) and establishing the protocol with appropriate doses and timing of the contrast medium administration.
METHODS
Thirty three goats were euthanized 10 to 300 min before the study. First, in 3 goats air was administered into the left or right common carotid artery at dose of 60, 100 and 120 ml/kg, and after each dose PMCT was performed in lateral recumbency. As the latter dose proved to visualize blood vessels best, following 30 goats were examined in the same manner but only with the use of air dose of 120 ml/kg. The quality of CT scans was evaluated independently by two board-certified radiologists.
RESULTS
In all studied animals the vascular system filled with air was clearly visualized on CT scans. In most of goats this amount of air revealed vessels smaller than 4 mm in diameter.
CONCLUSIONS
PMCT with air as a negative contrast agent may be an alternative technique used in post-mortem angiography.
目的
评估空气作为死后计算机断层扫描（PMCT）中血管负性对比介质的用途，并制定合适剂量和对比介质给药时间的方案。
方法
33 只山羊在研究前 10 至 300 分钟被安乐死。首先，在 3 只山羊中，以 60、100 和 120 ml/kg 的剂量将空气注入左或右颈总动脉，每次给药后在侧卧位进行 PMCT。由于后一个剂量证明可以最好地显示血管，随后对 30 只山羊以相同的方式进行检查，但仅使用 120 ml/kg 的空气剂量。两名经过委员会认证的放射科医生独立评估 CT 扫描的质量。
结果
在所有研究动物中，血管系统都在 CT 扫描中清晰可见。在大多数山羊中，这种数量的空气揭示了直径小于 4 毫米的血管。
结论
空气作为阴性对比剂的 PMCT 可能是死后血管造影中使用的替代技术。
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