Yushkova N A, Kholodkova E V, Korobova T S, Stanislavsky E S
Acta Microbiol Hung. 1986;33(2):147-56.
Antisera to extracellular slime glycolipoprotein of Pseudomonas aeruginosa of different O serogroups (immunotypes) show cross reactivity in passive haemagglutination (PHA) and agar gel immunoprecipitation test; cross reactivity is more distinct in PHA. Antisera to glycolipoprotein also have marked cross activity in mouse passive protection test against intraperitoneal challenge with 24 P. aeruginosa strains of different O groups including the toxigenic strain PA-103. On the basis of the results, glycolipoprotein producer P. aeruginosa strains may be selected in order to make a preparation for active and passive immunization against pseudomonas infection.
针对不同O血清群(免疫型)的铜绿假单胞菌细胞外黏液糖脂蛋白的抗血清,在被动血凝试验(PHA)和琼脂凝胶免疫沉淀试验中显示出交叉反应性;交叉反应性在PHA中更为明显。糖脂蛋白抗血清在针对包括产毒菌株PA - 103在内的24种不同O群铜绿假单胞菌菌株腹腔内攻击的小鼠被动保护试验中也具有显著的交叉活性。基于这些结果,可以选择产生糖脂蛋白的铜绿假单胞菌菌株,以制备针对假单胞菌感染的主动和被动免疫制剂。