Abe C, Shionoya H, Hirao Y, Okada K, Homma J Y
Jpn J Exp Med. 1975 Oct;45(5):355-9.
Prior immunization of mice with the protein moiety of the endotoxin (OEP) of Pseudomonas aeruginosa isolated by Homma and his associates [1, 2], can protect mice against infection with any of 21 standard strains belonging to Fisher's immunotypes and Homma's serotypes. It is also confirmed that there is found a significant protection in mice each injected with 0.1 ml of anti-OEP rabbit serum against challenge with each of 7 strains of Fisher's immunotypes. It has been revealed through the OEP-HA, agar gel diffusion and indirect fluorescent antibody tests that OEP is an antigen existing serologically in common in P. aeruginosa.
保坂和他的同事们[1,2]分离出的铜绿假单胞菌内毒素的蛋白质部分（OEP）预先免疫小鼠，可以保护小鼠免受属于费舍尔免疫型和保坂血清型的21种标准菌株中任何一种的感染。还证实，每只注射0.1ml抗OEP兔血清的小鼠在受到费舍尔免疫型的7种菌株中的每一种攻击时都有显著的保护作用。通过OEP-HA、琼脂凝胶扩散和间接荧光抗体试验已经表明，OEP是一种在铜绿假单胞菌中血清学上普遍存在的抗原。
