Parpa Efi, Kostopoulou Sotiria, Tsilika Eleni, Galanos Antonis, Mystakidou Kyriaki
1 Departmet of Radiology, Pain Relief and Palliative Care Unit, Areteion Hospital, National & Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Am J Hosp Palliat Care. 2019 Dec;36(12):1063-1067. doi: 10.1177/1049909119844783. Epub 2019 Apr 23.
The objectives of the study were to evaluate the relationship between depression, preparatory grief, and loss of dignity in patients with advanced cancer and whether depression has a mediator and/or a mediator role between preparatory grief and dignity. The participants were 120 patients with advanced cancer who completed the Greek version of the Patient Dignity Inventory, the Greek Hospital Anxiety and Depression Scale, and the Preparatory Grief in Advanced Cancer Patients questionnaire. Depression was highly correlated with preparatory grief and loss of dignity. Additionally, strong relationship was found between preparatory grief and loss of dignity. Mediation analyses revealed that preparatory grief influenced loss of dignity as well as indirectly by its effect on depression. However, there was not any affect of depression as moderator. The effect of depression on preparatory grief in patients with advanced cancer and dignity emphasizing the need for further research to confirm the current relationship as well as the need for treatment of depression.
本研究的目的是评估晚期癌症患者的抑郁、预备性悲伤和尊严丧失之间的关系，以及抑郁在预备性悲伤和尊严之间是否具有中介和/或调节作用。研究对象为120例晚期癌症患者，他们完成了希腊语版的患者尊严量表、希腊医院焦虑抑郁量表以及晚期癌症患者预备性悲伤问卷。抑郁与预备性悲伤和尊严丧失高度相关。此外，预备性悲伤和尊严丧失之间也存在密切关系。中介分析显示，预备性悲伤既直接影响尊严丧失，也通过其对抑郁的影响间接影响尊严丧失。然而，抑郁作为调节因素没有任何影响。抑郁对晚期癌症患者的预备性悲伤和尊严的影响强调了进一步研究以证实当前关系以及治疗抑郁的必要性。
