Christy Alison, Messacar Kevin
1 Alison Christy, Providence Health & Services, Pediatric Neurology, Portland, OR, USA.
2 University of Colorado, Denver, CO, USA.
J Child Neurol. 2019 Aug;34(9):511-516. doi: 10.1177/0883073819838376. Epub 2019 Apr 23.
Acute flaccid myelitis is a disease that affects the anterior horn cells of the spinal cord, leading to rapid onset of flaccid paralysis. Recent biennial epidemics, beginning in the summer of 2014, have been associated with enterovirus D68, although the underlying pathophysiology is unknown. Patients present with asymmetric flaccid weakness of the extremities, with cranial neuropathy and without encephalopathy, and often have residual disability. Here we review the current literature on this disabling disease and discuss treatment modalities and ongoing research.
急性弛缓性脊髓炎是一种影响脊髓前角细胞的疾病，可导致弛缓性麻痹迅速发作。始于2014年夏季的近期两年一次的疫情与肠道病毒D68有关，尽管其潜在病理生理学尚不清楚。患者表现为四肢不对称弛缓性无力，伴有颅神经病变且无脑病，并且常留有残疾。在此，我们综述了关于这种致残性疾病的当前文献，并讨论了治疗方式及正在进行的研究。
