Department of Pediatric Rehabilitation, Kennedy Krieger Institute, 707 North Broadway, Ste. 232, Baltimore, MD 21205, USA; Department of Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine.
Department of Pediatric Rehabilitation, Kennedy Krieger Institute, 707 North Broadway, Ste. 232, Baltimore, MD 21205, USA; Department of Pediatrics, Johns Hopkins University School of Medicine.
Phys Med Rehabil Clin N Am. 2021 Aug;32(3):477-491. doi: 10.1016/j.pmr.2021.02.004. Epub 2021 May 20.
Acute flaccid myelitis (AFM) is an incompletely understood neurologic disorder occurring in epidemic fashion causing weakness ranging from mild paresis to devastating paralysis in children and some adults. This article reviews the case definition of AFM as well as its epidemiology and association with enteroviral infection. The clinical presentation, diagnostic investigation with particular attention to electrodiagnostics, acute management, and surgical options are described. Clinical outcomes and considerations for acute and long-term rehabilitation management are discussed extensively based on review of current literature, highlighting avenues for further study.
急性弛缓性脊髓炎(AFM)是一种不完全了解的神经系统疾病,呈流行方式发生,可导致儿童和部分成人出现从轻度无力到严重瘫痪等不同程度的虚弱。本文回顾了 AFM 的病例定义及其流行病学和与肠道病毒感染的关联。本文还描述了其临床表现、诊断检查(特别关注电诊断)、急性处理以及手术选择。根据对现有文献的回顾,详细讨论了临床结果以及急性和长期康复管理的考虑因素,强调了进一步研究的途径。