Bazzano A N, Var C, Wilkosz D, Duggal R, Oberhelman R A
Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, 1440 Canal St., New Orleans, LA, 70112, USA.
National Institute of Public Health, #2 Kim Y Sung Blvd, Tuol Kork, P.O. Box 1300, Phnom Penh, Cambodia.
BMC Res Notes. 2019 Apr 24;12(1):236. doi: 10.1186/s13104-019-4265-5.
The aim of this study was to describe potential factors contributing to neonatal mortality in Takeo, Cambodia through assessment of verbal autopsies collected following newborn deaths in the community. The mortality review was nested within a trial of a behavioral intervention to improve newborn survival, and was conducted after the close of the trial, within the study setting. The World Health Organization standardized definition of neonatal mortality was employed, and two pediatricians independently reviewed data collected from each event to assign a cause of death.
Thirteen newborn deaths of infants born in health facilities participating in a community based, behavioral intervention were reported during February 2015-November 2016. Ten deaths (76.92%) were early neonatal deaths, two (15.38%) were late neonatal deaths, and one was a stillbirth. Five out of 13 deaths (38.46%) occurred within the first day of life. The largest single contributor to mortality was neonatal sepsis; six of 13 deaths (46.15%) were attributed to some form of sepsis. Twenty-three percent of deaths were attributed to asphyxia. The study highlights the continuing need to improve quality of care and infection prevention and control, and to fully address causes of sepsis, in order to effectively reduce mortality in the newborn period.
本研究旨在通过评估社区新生儿死亡后收集的口头尸检信息，描述柬埔寨茶胶省新生儿死亡的潜在影响因素。死亡率审查嵌套在一项旨在提高新生儿存活率的行为干预试验中，在试验结束后于研究地点内进行。采用了世界卫生组织新生儿死亡率的标准化定义，两名儿科医生独立审查从每个事件收集的数据以确定死因。
2015年2月至2016年11月期间，报告了参与基于社区的行为干预的医疗机构中出生的13例新生儿死亡病例。10例死亡（76.92%）为早期新生儿死亡，2例（15.38%）为晚期新生儿死亡，1例为死产。13例死亡中有5例（38.46%）发生在出生后第一天内。导致死亡的最大单一因素是新生儿败血症；13例死亡中有6例（46.15%）归因于某种形式的败血症。23%的死亡归因于窒息。该研究强调持续需要提高护理质量以及预防和控制感染，并全面解决败血症的病因，以有效降低新生儿期死亡率。
