Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology.
Division of Hematopathology, Department of Laboratory Medicine and Pathology.
Blood Adv. 2019 Apr 23;3(8):1298-1302. doi: 10.1182/bloodadvances.2019031450.
This article characterizes a cryptic rearrangement in MCL by NGS. Mate-pair sequencing can help in accurately diagnosing MCL in cases of cyclin-D1–positive B-cell lymphoma with negative FISH studies.
本文通过 NGS 对 MCL 中的隐匿性重排进行了特征描述。在 cyclin-D1 阳性、FISH 检测阴性的 B 细胞淋巴瘤中,通过使用 Mate-pair 测序有助于准确诊断 MCL。